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Related Concept Videos

Continuous Renal Replacement Therapy01:30

Continuous Renal Replacement Therapy

Continuous Renal Replacement Therapy, also known as CRRT, is a procedural treatment for acute kidney injury (AKI) that gradually removes uremic toxins and fluids while maintaining acid-base balance and stabilizing electrolytes. It is particularly useful for hemodynamically unstable patients. Unlike intermittent hemodialysis, which is faster, CRRT provides a gentler approach over 24 hours, closely mimicking the function of natural kidneys. However, CRRT is not ideal for patients with...
Extracorporeal Removal of Drugs: Continuous Renal Replacement Therapy01:26

Extracorporeal Removal of Drugs: Continuous Renal Replacement Therapy

Continuous Renal Replacement Therapy (CRRT) is an essential intervention for patients experiencing severe kidney dysfunction. This therapy offers a continuous mechanism for removing fluids and toxins from the bloodstream, leveraging the patient’s blood pressure to facilitate filtration through a specialized filter. This method contrasts with intermittent dialysis, providing a gentler and more consistent removal of waste products and excess fluid, which is particularly beneficial in critically...
Hemodialysis I: Introduction01:25

Hemodialysis I: Introduction

Hemodialysis (HD) is a medical treatment that artificially removes waste products, excess fluids, and toxins from the blood when the kidneys are no longer able to perform these functions effectively. In this process, blood is filtered through a semipermeable membrane, allowing for the selective removal of waste while preserving necessary components like blood cells and proteins. Hemodialysis is typically performed in patients with end-stage renal disease (ESRD) or severe kidney...
Hemodialysis II: Procedure and Complications01:24

Hemodialysis II: Procedure and Complications

DialyzersA hemodialysis (HD) dialyzer is a plastic cartridge containing thousands of parallel hollow fibers, which serve as semipermeable membranes. These fibers are typically made from cellulose-based or other synthetic materials. During HD, blood is pumped into the top of the cartridge and distributed among these fibers. Simultaneously, dialysis fluid, known as dialysate, is introduced into the bottom of the cartridge, bathing the outside of the fibers. Across the semipermeable membrane,...
Extracorporeal Removal of Drugs: Hemoperfusion and Hemofiltration01:25

Extracorporeal Removal of Drugs: Hemoperfusion and Hemofiltration

Hemoperfusion and hemofiltration are critical techniques in medical treatments to eliminate accumulated drugs, metabolites, and electrolytes from the bloodstream. These methods are particularly vital in cases of accidental poisoning and drug overdose.Hemoperfusion involves passing blood through an adsorbent material to remove unwanted substances. The main adsorbents used in hemoperfusion include activated charcoal and Amberlite resins. Activated charcoal can adsorb both polar and nonpolar...
Hemodialysis III: Nursing Management01:25

Hemodialysis III: Nursing Management

The nursing management of a patient undergoing hemodialysis includes several critical steps, starting with a thorough assessment before the procedure.Before the Hemodialysis ProcedureFirst, record the patient's vital signs—blood pressure, heart rate, respiratory rate, and temperature—to establish a baseline. This baseline is essential for detecting conditions such as hypotension that could impact the patient's response to dialysis. Document the patient's pre-dialysis weight, as this measurement...

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Related Experiment Video

Updated: Jul 19, 2026

Creating Radio-cephalic Arteriovenous Fistula in the Forearm with a Modified No-Touch Technique
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Creating Radio-cephalic Arteriovenous Fistula in the Forearm with a Modified No-Touch Technique

Published on: April 1, 2022

Clinical review: alternative vascular access techniques for continuous hemofiltration.

Joseph V DiCarlo1, Scott R Auerbach, Steven R Alexander

  • 1Division of Pediatric Critical Care Medicine, Stanford University School of Medicine, Welch Road, Palo Alto, California 94304, USA. jdicarlo@stanford.edu

Critical Care (London, England)
|September 23, 2006
PubMed
Summary

Securing vascular access for continuous hemofiltration is challenging in patients with organ failure. This study details techniques for infants and children, including ultrasound guidance, to overcome common access issues.

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Last Updated: Jul 19, 2026

Creating Radio-cephalic Arteriovenous Fistula in the Forearm with a Modified No-Touch Technique
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A Modified Technique for Arteriovenous Fistula Construction in Rabbits

Published on: February 10, 2023

Area of Science:

  • Nephrology
  • Critical Care Medicine
  • Pediatric Intensive Care

Background:

  • Vascular access for continuous hemofiltration presents challenges in critically ill patients, particularly those with edema or coagulopathy.
  • Common issues include venous obstruction, cannulation difficulties, bleeding risks, and circuit clotting from disseminated intravascular coagulation.

Purpose of the Study:

  • To describe practical techniques for obtaining and maintaining vascular access for continuous hemofiltration in challenging patient populations.
  • To address specific difficulties encountered in infants, children, and adults with organ failure.

Main Methods:

  • Description of a two-single-lumen thin-walled vascular sheath technique for infant access.
  • Explanation of the 'mini-introducer' technique for infants and small children with edema or poor perfusion.
  • Review of alternative access routes, ultrasound guidance, and specific venous return options (umbilical, antecubital veins).

Main Results:

  • The described techniques aim to facilitate secure vascular access, overcoming challenges like edema, coagulopathy, and anatomical difficulties.
  • Ultrasound guidance is highlighted as a crucial tool for safe and effective cannulation of central veins.
  • Alternative access strategies provide options for various age groups and clinical scenarios.

Conclusions:

  • Effective vascular access for continuous hemofiltration can be achieved through specialized techniques and careful consideration of patient-specific factors.
  • These methods improve the feasibility and safety of hemofiltration in critically ill patients, including infants and children.
  • The review provides a comprehensive guide to vascular access options in challenging hemofiltration cases.