Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Erectile dysfunction predicts generalised cardiovascular disease: evidence from a case-control study.

Bronwyn G A Stuckey1, John P Walsh, Helena L Ching

  • 1Keogh Institute for Medical Research, Nedlands, WA, Australia. bstuckey@cyllene.uwa.edu.au

Atherosclerosis
|September 23, 2006
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Genomic analyses implicate hormonal and metabolic dysregulation in polycystic ovary syndrome.

Nature genetics·2026
Same author

Characterization of distinct polycystic ovary syndrome subtypes by cluster and principal component analyses.

Frontiers in endocrinology·2025
Same author

Testosterone Treatment and Sexual Function in Men: Secondary Analysis of the T4DM (Testosterone for Diabetes) Trial.

The Journal of clinical endocrinology and metabolism·2025
Same author

Response to Letter to the Editor From Lin et al: "Testosterone Treatment, Weight Loss, and Health-Related Quality of Life and Psychosocial Function in Men: A 2-Year Randomized Controlled Trial".

The Journal of clinical endocrinology and metabolism·2025
Same author

Predicting type 2 diabetes and testosterone effects in high-risk Australian men: development and external validation of a 2-year risk model.

European journal of endocrinology·2024
Same author

Reflections on The Lancet menopause Series.

Lancet (London, England)·2024

Men with idiopathic erectile dysfunction (ED) show signs of vascular and autonomic dysfunction, suggesting ED may predict future cardiovascular disease.

Area of Science:

  • Cardiovascular Medicine
  • Urology
  • Endocrinology

Background:

  • Idiopathic erectile dysfunction (ED) often lacks clear cardiovascular links.
  • Investigating subclinical vascular and autonomic dysfunction in ED is crucial.

Purpose of the Study:

  • To assess vascular and autonomic function in men with idiopathic ED.
  • To determine if ED is associated with subclinical cardiovascular dysfunction.

Main Methods:

  • Compared 49 men with ED to 50 controls (aged 40-70).
  • Assessed macrovascular endothelial function (brachial artery ultrasonography) and microvascular function (venous occlusion plethysmography).
  • Measured blood pressure and heart rate variability (30:15 RR ratio).

Main Results:

Related Experiment Videos

  • ED group had higher standing pulse pressure and lower 30:15 RR ratio.
  • Forearm reactive hyperemia showed impaired microvascular function in the ED group.
  • No significant difference in brachial artery flow-mediated dilation.

Conclusions:

  • Idiopathic ED is linked to endothelial dysfunction in resistance vessels.
  • ED is associated with increased pulse pressure and impaired heart rate variability.
  • Erectile dysfunction may serve as an early predictor of cardiovascular disease.