Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

CW-OSL measurement protocols using optical fibre Al2O3:C dosemeters.

J M Edmund1, C E Andersen, C J Marckmann

  • 1Risø National Laboratory, Radiation Research Department, DK-4000 Roskilde, Denmark. jens.edmund@risoe.dk

Radiation Protection Dosimetry
|September 23, 2006
PubMed
Summary

A new in vivo dosimetry system uses carbon-doped aluminium oxide (Al2O3:C) crystals and continuous wave optically stimulated luminescence (CW-OSL) for accurate radiotherapy dose measurement. The protocol enhances reproducibility and linearity by analyzing specific luminescence decay components.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Accumulated dose implications from systematic dose-rate transients in gated treatments with Viewray MRIdian accelerators.

Biomedical physics & engineering express·2023
Same author

Proton Beam Therapy in the Reirradiation Setting of Brain and Base of Skull Tumour Recurrences.

Clinical oncology (Royal College of Radiologists (Great Britain))·2023
Same author

Assessing Equity of Access to Proton Beam Therapy: A Literature Review.

Clinical oncology (Royal College of Radiologists (Great Britain))·2023
Same author

Outcomes of Patients Treated in the UK Proton Overseas Programme: Central Nervous System Group.

Clinical oncology (Royal College of Radiologists (Great Britain))·2023
Same author

A magnetoencephalography study of first-time mothers listening to infant cries.

Cerebral cortex (New York, N.Y. : 1991)·2022
Same author

Reading the Mind of a Machine: Hopes and Hypes of Artificial Intelligence for Clinical Oncology Imaging.

Clinical oncology (Royal College of Radiologists (Great Britain))·2021

Area of Science:

  • Medical Physics
  • Radiation Oncology
  • Dosimetry

Background:

  • Accurate in vivo dosimetry is crucial for effective radiotherapy.
  • Traditional dosimetry methods face challenges in real-time dose monitoring.
  • Carbon-doped aluminium oxide (Al2O3:C) offers potential for luminescence-based dosimetry.

Purpose of the Study:

  • To introduce and validate a new system for in vivo dosimetry during radiotherapy.
  • To establish a reproducible and linear measurement protocol for clinical application.
  • To optimize the analysis of luminescence signals for precise dose determination.

Main Methods:

  • Utilized a novel system employing Al2O3:C crystals and optical fibers for signal transmission.
  • Employed continuous wave optically stimulated luminescence (CW-OSL) with a 532 nm laser.

Related Experiment Videos

  • Developed a measurement protocol involving signal stabilization with a minimum pre-dose and analysis of luminescence decay components.

    • Main Results:

    • Demonstrated high reproducibility and improved linearity of the CW-OSL measurement protocol.
    • Identified the necessity of a crystal-specific minimum pre-dose for signal stabilization.
    • Showcased the effectiveness of separating decay curves into components, utilizing only fast and medium components for accurate measurement.

    Conclusions:

    • The developed CW-OSL system and protocol are suitable for clinical in vivo dosimetry.
    • Optimized signal processing, including component analysis of decay curves, is essential for accurate dose measurement.
    • This advancement offers a promising tool for real-time radiotherapy dose monitoring and quality assurance.