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Breast carcinomas: why are they missed?

M Muttarak¹, S Pojchamarnwiputh, B Chaiwun

¹Department of Radiology, Chiang Mai University, 110 Intavaroros Road, Chiang Mai 50200, Thailand. mmuttara@mail.med.cmu.ac.th

Singapore Medical Journal

|September 23, 2006

Summary

Mammography can miss breast cancers, with dense tissue and interpretation errors being common causes. Identifying these factors can help reduce delayed diagnoses and improve patient outcomes.

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Area of Science:

Radiology
Oncology
Medical Imaging

Background:

Mammography is a key tool for early breast cancer detection.
A significant percentage of breast cancers are missed by mammography.
Delayed diagnosis negatively impacts patient prognosis.

Purpose of the Study:

To identify the causes and characteristics of breast cancers missed by mammography.
To reduce the rate of missed breast cancer diagnoses.

Main Methods:

Review of 13,191 mammograms over five years.
Utilized Breast Imaging Reporting and Data Systems (BI-RADS) for assessment.
Cross-referenced mammogram reports with histological diagnoses.

Main Results:

18 out of 344 (5.2%) breast cancers were missed by mammography.
Causes included dense breast tissue (5), perception/interpretation errors (11), unusual lesion characteristics (1), and poor positioning (1).

Conclusions:

Dense breast parenchyma obscuring lesions is a significant factor.
Perception and interpretation errors contribute to missed diagnoses.
Poor technique and unusual lesion characteristics also play a role.

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Last Updated: Jul 19, 2026

Studying Triple Negative Breast Cancer Using Orthotopic Breast Cancer Model

Studying Triple Negative Breast Cancer Using Orthotopic Breast Cancer Model

Published on: March 20, 2020