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Related Concept Videos

Reliability and Validity01:29

Reliability and Validity

Reliability and validity are two important considerations that must be made with any type of data collection. Reliability refers to the ability to consistently produce a given result. In the context of psychological research, this would mean that any instruments or tools used to collect data do so in consistent, reproducible ways.

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Related Experiment Video

Updated: Jul 19, 2026

Establishment of Orthotopic Patient-derived Xenograft Models for Brain Tumors using a Stereotaxic Device
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Establishment of Orthotopic Patient-derived Xenograft Models for Brain Tumors using a Stereotaxic Device

Published on: May 2, 2025

The PedsQL Brain Tumor Module: initial reliability and validity.

Stephanie N Palmer1, Kathleen A Meeske, Ernest R Katz

  • 1Childrens Center for Cancer and Blood Diseases, Childrens Hospital Los Angeles, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.

Pediatric Blood & Cancer
|September 23, 2006
PubMed
Summary

The Pediatric Quality of Life Inventory (PedsQL) Brain Tumor Module shows good reliability and validity for assessing quality of life in children with brain tumors. This tool helps measure the health outcomes for pediatric cancer patients.

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Translational Brain Mapping at the University of Rochester Medical Center: Preserving the Mind Through Personalized Brain Mapping
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Translational Brain Mapping at the University of Rochester Medical Center: Preserving the Mind Through Personalized Brain Mapping

Published on: August 12, 2019

Area of Science:

  • Pediatric Oncology
  • Health Outcomes Research
  • Psychometrics

Background:

  • Brain tumors are the most common pediatric cancer after leukemia, with improving survival rates.
  • Increased survival necessitates a focus on quality of life as a critical health outcome.
  • The Pediatric Quality of Life Inventory (PedsQL) Brain Tumor Module is a tool designed to assess this.

Purpose of the Study:

  • To evaluate the internal consistency reliability of the PedsQL Brain Tumor Module.
  • To assess the construct validity of the PedsQL Brain Tumor Module.
  • To determine the measurement properties of this quality of life instrument for pediatric brain tumor patients.

Main Methods:

  • Administered PedsQL 4.0 Generic Core Scales, Fatigue Scale, and Brain Tumor Module to 99 families.
  • Sample included children aged 2-18 with various tumor locations and treatment statuses.
  • Data collected from parent proxy-reports and child self-reports.

Main Results:

  • Demonstrated strong internal consistency reliability for the PedsQL Brain Tumor Module (average alpha=0.78-0.92 for parents, 0.76-0.87 for children).
  • Supported construct validity through analysis of correlations with Generic Core Scales and Fatigue Scale.
  • The module's measurement properties were confirmed.

Conclusions:

  • The PedsQL Brain Tumor Module exhibits favorable measurement properties.
  • Findings support its use in assessing quality of life for pediatric brain tumor survivors.
  • This validates the tool for research and clinical practice in pediatric neuro-oncology.