[The lymphatic system of the liver in alcoholic intoxication]

Liver of men and test animals (dogs, white rats) has been studied by means of a complex of injection, histological and electron microscopical methods (179 organs). At alcoholic intoxication all elements of the lymphatic bed (capillaries, postcapillaries, lymphangions) demonstrate certain adaptive-compensatory or pathological changes. Their manifestation degree depends on duration of alcoholization (in the experiment--up to 7 months). The greatest changes are noted in the hepatic lymphatic bed of adolescents and of the first mature age. In the test animals the functional rearrangement is demonstrated as certain changes of lymph outflow via the thoracic duct, which was wider than in the control during the whole period of the experiment. A high resistivity of the lymphatic bed, activation of its function, absence of any parallelism between the morphological and functional rearrangements in the lymphatic bed have been revealed. Certain parallelism is noted in development of the morphological rearrangements between the lymphatic and circulatory links of the hepatic vascular bed and cell elements of the organ.