Related Experiment Video
Updated: Jul 19, 2026

Investigating the Alleviating Effects of Bacillus cereus Administration on Colitis through Gut Microbiota Modulation
Published on: July 27, 2022
[Therapeutic possibilities of probiotics in antibiotic-related diarrhea]
1Lehrstuhl für Ernährungsmedizin/Prävention, Universität Hohenheim. kraemers@uni-hohenheim.de
Abstract:
One of the major problems associated with the use of antibiotics is the occurrence of antibiotic-related diarrhea. Although most such cases of diarrhea are harmless, in individual cases it may lead on to fulminant colitis. In 10-20% of the patients, the causal factor is infection with Clostridium difficile, which multiplies unhindered in patients on antibiotics. In the meantime, controlled, randomized studies have shown that probiotics can exercise a preventive effect in antibiotic-related diarrhea. The administration of Saccharomyces boulardii or Lactobacillus rhamnosus GG reduces the relative risk of an antibiotic-related diarrhea developing by 0.5. The data are more uniform in children than in adults.
Related Concept Videos
Microbiota Modulation by Antibiotics
Drugs Affecting GI Tract Motility: Antimicrobials as Antidiarrheal Agents
Probiotics
Dysbiosis of the Gut Microbiota
Drugs for Treatment of Diarrhea-Predominant IBS
Two specific drugs used in the treatment are alosetron (Lotronex) and eluxadoline (Viberzi). Alosetron, a 5-HT3 antagonist, works by slowing the movement of stools in the gut, reducing bowel...
Inflammatory Bowel Disease IV: Pharmacological Management
Pharmacologic...
