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Serum endostatin levels in gastric cancer patients: correlation with clinicopathological parameters
Mahmut Koç1, Erdal Göçmen, Mehmet Kiliç
1Fifth Department of Surgery, Ankara Numune Education and Research Hospital, Ankara, Turkey.
Background/Aims:
The aim of this study was to evaluate the predictive role of the circulating levels of endostatin in gastric cancer patients.
Methodology:
This study is a retrospective case-control study. We measured serum endostatin levels of 30 patients aged between 34-83 years with gastric cancer and 30 patients without malignant pathology operated for benign pathologies with age ranging from 18 to 69.
Results:
Serum levels of endostatin were correlated with the Lauren classification. Significantly higher serum endostatin levels were obtained in Lauren intestinal type tumors than Lauren diffuse type tumors.
Conclusions:
These data suggest that serum endostatin levels do not correlate with clinicopathological parameters, except tumor histopathology (according to Lauren classification), in gastric cancer patients.