Five-year survival-after first-ever stroke

Dzevdet Smajlović1, Biljana Kojić, Osman Sinanović

  • 1Department of Neurology, University Clinical Centre, Faculty of Medicine, University of Tuzla, Trnovac bb, 75 000 Tuzla, Bosnia and Herzegovina.

Insights

Five-year survival rates for ischemic stroke and intracerebral hemorrhage are similar overall. However, patients surviving the first 30 days after intracerebral hemorrhage show better long-term outcomes.

Area of Science:

  • Neurology
  • Cardiovascular Medicine
  • Public Health

Background:

  • Stroke, encompassing ischemic stroke and intracerebral hemorrhage, remains a leading cause of mortality and long-term disability worldwide.
  • Understanding long-term survival patterns is crucial for effective patient management and public health strategies.
  • Previous studies have often focused on short-term outcomes or specific stroke subtypes, necessitating comprehensive analysis of 5-year survival for both major stroke types.

Purpose of the Study:

  • To analyze and compare the 5-year survival rates following first-ever ischemic stroke and intracerebral hemorrhage.
  • To identify factors influencing long-term mortality in stroke survivors.
  • To evaluate survival differences based on initial stroke type and early survival status.

Main Methods:

  • A retrospective analysis of 836 patients admitted with a first-ever stroke (ischemic or intracerebral hemorrhage) between 1997 and 1998.
  • Exclusion of subarachnoid hemorrhages.
  • Periodic follow-up examinations for surviving patients, with a final assessment at 5 years post-stroke.

Main Results:

  • Overall 30-day case-fatality was 36%, significantly higher for intracerebral hemorrhage (58.3%) than ischemic stroke (27.9%).
  • After 5 years, cumulative survival was 29%, with 31% of ischemic stroke patients and 24% of intracerebral hemorrhage patients alive.
  • Among 30-day survivors, 5-year survival was better for intracerebral hemorrhage (57%) compared to ischemic stroke (42.5%). Older age and hypertension were predictors of mortality for both stroke types.

Conclusions:

  • Long-term survival after first-ever ischemic stroke and intracerebral hemorrhage is comparable.
  • Intracerebral hemorrhage patients who survive the initial 30-day period demonstrate a better 5-year survival rate compared to their ischemic stroke counterparts.
  • Age and comorbidities like hypertension, heart disease, and diabetes significantly impact long-term stroke survival.

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