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Updated: Jul 19, 2026

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
Published on: January 18, 2018
Five-year survival-after first-ever stroke
Dzevdet Smajlović1, Biljana Kojić, Osman Sinanović
1Department of Neurology, University Clinical Centre, Faculty of Medicine, University of Tuzla, Trnovac bb, 75 000 Tuzla, Bosnia and Herzegovina.
Insights
Five-year survival rates for ischemic stroke and intracerebral hemorrhage are similar overall. However, patients surviving the first 30 days after intracerebral hemorrhage show better long-term outcomes.
Area of Science:
- Neurology
- Cardiovascular Medicine
- Public Health
Background:
- Stroke, encompassing ischemic stroke and intracerebral hemorrhage, remains a leading cause of mortality and long-term disability worldwide.
- Understanding long-term survival patterns is crucial for effective patient management and public health strategies.
- Previous studies have often focused on short-term outcomes or specific stroke subtypes, necessitating comprehensive analysis of 5-year survival for both major stroke types.
Purpose of the Study:
- To analyze and compare the 5-year survival rates following first-ever ischemic stroke and intracerebral hemorrhage.
- To identify factors influencing long-term mortality in stroke survivors.
- To evaluate survival differences based on initial stroke type and early survival status.
Main Methods:
- A retrospective analysis of 836 patients admitted with a first-ever stroke (ischemic or intracerebral hemorrhage) between 1997 and 1998.
- Exclusion of subarachnoid hemorrhages.
- Periodic follow-up examinations for surviving patients, with a final assessment at 5 years post-stroke.
Main Results:
- Overall 30-day case-fatality was 36%, significantly higher for intracerebral hemorrhage (58.3%) than ischemic stroke (27.9%).
- After 5 years, cumulative survival was 29%, with 31% of ischemic stroke patients and 24% of intracerebral hemorrhage patients alive.
- Among 30-day survivors, 5-year survival was better for intracerebral hemorrhage (57%) compared to ischemic stroke (42.5%). Older age and hypertension were predictors of mortality for both stroke types.
Conclusions:
- Long-term survival after first-ever ischemic stroke and intracerebral hemorrhage is comparable.
- Intracerebral hemorrhage patients who survive the initial 30-day period demonstrate a better 5-year survival rate compared to their ischemic stroke counterparts.
- Age and comorbidities like hypertension, heart disease, and diabetes significantly impact long-term stroke survival.
Abstract:
The aim of the study was to analyze the 5-year survival after first-ever ischemic stroke and intracerebral hemorrhage. In this study 836 patients were analyzed with a first-ever stroke admitted at the Department of Neurology Tuzla, Bosnia and Herzegovina, from January 1(st) 1997 to December 31(st) 1998. Of these 613 (73,3%) were ischemic strokes and 223 intracerebral hemorrhages (26,7%) Subarachnoid hemorrhages were excluded. After hospitalization surviving patients examined periodically, and a final examination was performed 5 years after the stroke. Overall, case-fatility at the first month was 36% (301/836) and the mortality rate was significantly higher in the patients with intracerebral hemorrhage (58,3% vs. 27,9%, p<0,0001). The first year survived 60% patients with ischemic stroke, and 38% with intracerebral hemorrhage. After 5 years, 188 (31%) patients with ischemic stroke and 53 (24%) with intracerebral hemorrhage were alive (p=0,5), and the cumulative survival rate for the entire study was 29%. Among 30-day survivors (n=535) surviving rate after 5 years was significantly higher in patients with intracerebral hemorrhage (57% vs. 42,5%, p=0,01). The survival rate was the highest for those 50 years and younger (57%), and the lowest for those aged over 70 years (9%). Predictors of 5-year mortality were older age and hypertension for both types of stroke, heart diseases for ischemic stroke and diabetes for intracerebral hemorrhage. Long-term survival after first-ever ischemic stroke and intracerebral hemorrhage is similar. However, among 30-day survivors the 5-year survival is better in patients with intracerebral hemorrhage.
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Hemorrhagic Stroke ll: Pathophysiology
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