Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Elevated acute phase reactants in hemodialysis patients.

D Docci1, R Bilancioni, L Baldrati

  • 1Servizio di Nefrologia e Dialisi, Ospedale M. Bufalini, Cesena, Italy.

Clinical Nephrology
|August 1, 1990
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Naturally occurring asbestos in Southern Italy: Geological and mineralogical investigation of fibrous antigorite from Calabrian serpentinites in view of its hazard assessment.

The Science of the total environment·2025
Same author

Efficient Spin Torques in Antiferromagnetic CoO/Pt Quantified by Comparing Field- and Current-Induced Switching.

Physical review letters·2020
Same author

Hydroxyl radicals and oxidative stress: the dark side of Fe corrosion.

Colloids and surfaces. B, Biointerfaces·2019
Same author

Mechanism of Néel Order Switching in Antiferromagnetic Thin Films Revealed by Magnetotransport and Direct Imaging.

Physical review letters·2019
Same author

Spin structure and spin Hall magnetoresistance of epitaxial thin films of the insulating non-collinear antiferromagnet SmFeO<sub>3</sub>.

Journal of physics. Condensed matter : an Institute of Physics journal·2019
Same author

Tunable long-distance spin transport in a crystalline antiferromagnetic iron oxide.

Nature·2018
Same journal

Clinical characteristics and outcomes of adults with minimal change disease: A retrospective, cross-sectional study.

Clinical nephrology·2026
Same journal

Analysis of end-stage renal disease mediated by cuproptosis-related genes.

Clinical nephrology·2026
Same journal

The relationship between red cell distribution width and platelet ratio in acute kidney injury among ventilator-associated pneumonia patients: A MIMIC-IV database study.

Clinical nephrology·2026
Same journal

Arterial stiffness and choroidal vascularity index in autosomal dominant polycystic kidney disease with preserved kidney function.

Clinical nephrology·2026
Same journal

Antibody-drug conjugate therapy in a renal transplant patient with bladder cancer: A case report.

Clinical nephrology·2026
Same journal

Epigenetic age enhances eGFR-based prediction of all-cause mortality: A cross-cohort validation of a novel risk model.

Clinical nephrology·2026
See all related articles

C-reactive protein is often elevated in hemodialysis patients, unlike alpha-1-acid glycoprotein and alpha-1-proteinase inhibitor, which maintain specificity. Haptoglobin may be unreliable due to false positives.

Area of Science:

  • Clinical Chemistry
  • Nephrology
  • Immunology

Background:

  • Acute phase reactants are key indicators of inflammation.
  • Hemodialysis patients may exhibit altered levels of acute phase proteins.
  • Assessing specificity of acute phase reactants in hemodialysis is crucial.

Purpose of the Study:

  • To evaluate the incidence of elevated acute phase reactants in hemodialysis patients.
  • To compare these levels with healthy controls.
  • To determine the specificity of certain acute phase reactants during hemodialysis.

Main Methods:

  • Nephelometry was used to measure acute phase reactants.
  • 69 hemodialysis patients and 30 healthy subjects were included.
  • Levels of C-reactive protein, haptoglobin, alpha-1-acid glycoprotein, and alpha-1-proteinase inhibitor were assessed.

Related Experiment Videos

Main Results:

  • Elevated C-reactive protein was observed in 40.6% of patients, correlating with hemodialysis duration.
  • Haptoglobin was elevated in 33.3% of patients.
  • Alpha-1-acid glycoprotein and alpha-1-proteinase inhibitor showed no significant difference compared to controls.

Conclusions:

  • C-reactive protein is a sensitive but potentially non-specific marker in hemodialysis.
  • Alpha-1-acid glycoprotein and alpha-1-proteinase inhibitor demonstrate high specificity in hemodialysis patients.
  • Haptoglobin may be unreliable as an acute phase reactant in this population due to false positives.