Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Interictal spike detection comparing subdural and depth electrodes during electrocorticography.

M D Privitera1, J G Quinlan, H S Yeh

  • 1Department of Neurology, University of Cincinnati Medical Center, OH 45267-0525.

Electroencephalography and Clinical Neurophysiology
|November 1, 1990
PubMed
Summary

Subdural and depth electrodes offer complementary insights for detecting and localizing temporal lobe interictal epileptiform discharges (IEDs). Neither electrode type demonstrated superiority in pinpointing IEDs within the temporal lobe.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Randomized dose-controlled study of topiramate as first-line therapy in epilepsy.

Acta neurologica Scandinavica·2005
Same author

Valproic acid blood genomic expression patterns in children with epilepsy - a pilot study.

Acta neurologica Scandinavica·2004
Same author

An open-label study of levetiracetam at individualised doses between 1000 and 3000 mg day(-1) in adult patients with refractory epilepsy.

Seizure·2003
Same author

Topiramate, carbamazepine and valproate monotherapy: double-blind comparison in newly diagnosed epilepsy.

Acta neurologica Scandinavica·2003
Same author

Vagus nerve stimulation for partial seizures.

The Cochrane database of systematic reviews·2002
Same author

Long-term evaluation of extended thymectomy with anterior mediastinal dissection for myasthenia gravis.

Surgery·2001

Area of Science:

  • Neurosurgery
  • Epileptology
  • Neurophysiology

Background:

  • Accurate localization of interictal epileptiform discharges (IEDs) is crucial for epilepsy surgery.
  • Temporal lobe epilepsy (TLE) is a common form of medically intractable epilepsy.
  • Evaluating electrode efficacy in IED detection is vital for surgical planning.

Purpose of the Study:

  • To compare the efficacy of subdural and depth electrodes in detecting and localizing temporal lobe IEDs.
  • To assess whether electrode type influences the ability to differentiate mesial vs. lateral or anterior vs. posterior IEDs.
  • To determine if subdural and depth electrodes provide complementary localization data.

Main Methods:

  • Simultaneous intraoperative recordings using both subdural and depth electrodes in 16 patients.

Related Experiment Videos

  • Patients underwent anterior temporal lobe resections for medically intractable seizures under local anesthesia.
  • Analysis of IED detection and localization patterns based on electrode contact engagement.

    • Main Results:

    • Focal IEDs were detected at the nearest contact for both electrode types.
    • Regional IEDs appeared simultaneously across both subdural and depth electrodes.
    • Neither electrode type was superior in determining the mesial/lateral or anterior/posterior location of IEDs.

    Conclusions:

    • Subdural and depth electrodes provide complementary information for temporal lobe IED localization.
    • Both electrode types are valuable tools, with distinct strengths in detecting focal versus regional discharges.
    • Combined use of subdural and depth electrodes may enhance the comprehensive understanding of IEDs in TLE.