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Porphyrin-Modified Beads for Use as Compensation Controls in Flow Cytometry
Published on: March 24, 2023
Study on synthesis and biological activity of a galactosylated piperazinyl porphyrin
1College of Chemical and Environmental Engineering, Changsha University of Science and Technology, Changsha 410076, China. lihepinghn@163.com
Bioorganic & Medicinal Chemistry Letters
|September 26, 2006
Abstract:
In order to obtain an carcinoma-selective drug, the synthesis and characterization of 5,10,15,20-tetra[4-(4'-galactosylpiperazinyl)phenyl]porphyrin (TGPP) is reported. The biological activity on cancer cells and the pharmacokinetics are also reported as preliminary results showing a very high liver to skin ratio and short retention time in tissues, and thus promising activity in photodynamic therapy.
