Related Experiment Video

Updated: Jul 19, 2026

An Improved and High Throughput Respiratory Syncytial Virus (RSV) Micro-neutralization Assay
09:14

An Improved and High Throughput Respiratory Syncytial Virus (RSV) Micro-neutralization Assay

Published on: January 26, 2019

Efforts at rubella elimination in the United States: the impact of hemispheric rubella control

Gustavo H Dayan1, Carlos Castillo-Solórzano, Margarita Nava

  • 1National Center for Immunization and Respiratory Diseases (proposed), Centers for Disease Control and Prevention, Atlanta, GA 30333, USA. gdayan@cdc.gov

Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America
|September 26, 2006
PubMed

Insights

Hemispheric rubella control initiatives, especially in Mexico, significantly reduced rubella cases. This public health effort appears to have facilitated rubella elimination in the United States by 2004.

Area of Science:

  • Public Health
  • Epidemiology
  • Vaccinology

Background:

  • Rubella (German measles) posed a significant public health concern globally.
  • Maintaining high vaccination coverage is crucial for preventing rubella outbreaks.

Purpose of the Study:

  • To assess the impact of rubella control in the Americas on rubella elimination in the United States.
  • To analyze rubella vaccination trends, surveillance data, and disease patterns from 1997-2004.

Main Methods:

  • Retrospective analysis of reported rubella cases in the Americas, Mexico, and the United States.
  • Examination of rubella vaccination coverage and control initiative data during the study period.

Main Results:

  • Reported rubella cases in the Americas decreased from 130,375 in 1997 to 3103 in 2004.
  • Mexico administered approximately 77.7 million rubella-containing vaccine doses as part of a larger regional initiative.
  • Rubella cases in the U.S. dropped from 817 (1997-1999) to below 25 cases annually by 2001, indicating elimination.

Conclusions:

  • Rubella control strategies implemented across the Americas, notably in Mexico, played a crucial role in achieving rubella elimination in the United States.
  • The success highlights the importance of regional cooperation in infectious disease control and elimination efforts.

More Related Videos

Enhanced Rabies Surveillance Using a Direct Rapid Immunohistochemical Test08:58

Enhanced Rabies Surveillance Using a Direct Rapid Immunohistochemical Test

Published on: April 30, 2019

Developing a Salivary Antibody Multiplex Immunoassay to Measure Human Exposure to Environmental Pathogens09:08

Developing a Salivary Antibody Multiplex Immunoassay to Measure Human Exposure to Environmental Pathogens

Published on: September 12, 2016

Related Concept Videos

Smallpox01:24

Smallpox

Smallpox is a severe contagious disease caused by the Variola major virus, a double-stranded DNA member of the Poxviridae family.Variola major transmission occurs primarily via inhalation of virus-laden droplets or direct contact with infectious scabs. The incubation period averages approximately seven days, although it may range from 7 to 17 days depending on the inoculum and host factors.Clinically, the prodromal phase is marked by an abrupt onset of high fever, malaise, headache, and myalgia.
Respiratory Syncytial Virus Disease01:29

Respiratory Syncytial Virus Disease

Human respiratory syncytial virus (RSV) is a widespread pathogen that primarily targets infants and young children but also poses a serious health risk to elderly and immunocompromised individuals. Belonging to the Pneumoviridae family, RSV is a negative-sense, single-stranded RNA virus within the Pneumovirus genus. Its global health burden is significant, with millions of cases annually resulting in hospitalizations and mortality, particularly in resource-limited settings. Although most...
Rh Blood Group01:19

Rh Blood Group

The Rhesus (Rh) antigen is crucial in determining blood groups and ensuring compatibility during blood transfusions.
Vaccinations01:51

Vaccinations

Overview
Poliomyelitis01:17

Poliomyelitis

Poliomyelitis is caused by poliovirus, a small, non-enveloped, positive-sense RNA virus of the Picornaviridae family and Enterovirus genus. Transmission occurs primarily via the fecal-oral route, often through ingestion of contaminated water or food. The virus initially replicates in the oropharynx and intestinal mucosa, particularly in lymphoid tissues such as the tonsils, Peyer’s patches, and regional lymph nodes. Primary viremia follows, allowing dissemination throughout the body.In most...
Cytomegalovirus Disease01:27

Cytomegalovirus Disease

Cytomegalovirus (CMV) disease is caused by human cytomegalovirus, a double-stranded DNA virus of the Herpesviridae family. While primary CMV infection is often asymptomatic in immunocompetent individuals, the virus can cause severe disease in neonates and immunocompromised patients. CMV is the most common cause of congenital viral infection in the United States, and a major pathogen in solid organ and hematopoietic stem cell transplant recipients.CMV is transmitted via bodily fluids, sexual...