Related Experiment Video
Updated: Jul 19, 2026

Systematic Approach to Identify Novel Antimicrobial and Antibiofilm Molecules from Plants' Extracts and Fractions to Prevent Dental Caries
Published on: March 31, 2021
Anticaries potential of a stabilized stannous fluoride/sodium hexametaphosphate dentifrice
Aaron M Pfarrer1, Christina M McQueen, Michelle A Lawless
1The Procter & Gamble Company, Health Care Research Center, Mason, Ohio, USA.
Abstract:
The objective of this research was to evaluate the anticaries potential of stabilized stannous fluoride and sodium hexametaphosphate dentifrice using a series of laboratory studies. In a study of fluoride uptake into demineralized enamel, the stannous fluoride/sodium hexametaphosphate dentifrice exhibited fluoride uptake comparable to the clinically proven stannous fluoride and silica dentifrice. Under lesion progression pH-cycling conditions, the stabilized stannous fluoride/sodium hexametaphosphate dentifrice was shown to protect teeth against lesion initiation and progression almost completely, and was comparable to conventional, clinically proven dentifrices. This series of well-controlled and validated in vitro studies demonstrates the anticaries potential of the stabilized stannous fluoride/sodium hexametaphosphate dentifrice. These in vitro results suggest that the stabilized stannous fluoride/sodium hexametaphosphate dentifrice may provide enhanced anticaries performance relative to a sodium fluoride control dentifrice. These results are reflective of the clinical benefits previously reported for stabilized stannous fluoride/sodium hexametaphosphate dentifrices.
More Related Videos
08:21Optimized Procedure for Determining the Adsorption of Phosphonates onto Granular Ferric Hydroxide using a Miniaturized Phosphorus Determination Method
Published on: May 18, 2018
08:26Development of Amelogenin-chitosan Hydrogel for In Vitro Enamel Regrowth with a Dense Interface
Published on: July 10, 2014
Related Concept Videos
EDTA: Chemistry and Properties
Crown Ethers
Solubility Equilibria: Overview
Solubility is important in biological and environmental processes. A notable...
ortho–para-Directing Deactivators: Halogens
Masking and Demasking Agents
There are many masking agents, such as cyanide, fluoride, triethanolamine, thiourea, and 2,3-bis(sulfanyl)propan-1-ol (formerly 2,3-dimercapto-1-propanol), with the masking agent chosen based on the metal...
Factors Affecting Solubility