Related Experiment Video
Updated: Jul 19, 2026
05:28
Standard Membrane Feeding Assay for the Detection of Plasmodium falciparum Infection in Anopheles Mosquito Vectors
Published on: May 12, 2022
[Filariasis control: entry point for other helminthiasis control programs?].
1l'Institut de recherche pour le développement (IRD)-UR-024, Paris, France. boussinesq@ird.fr
Medecine Tropicale : Revue Du Corps De Sante Colonial
|September 27, 2006
Summary
Community-directed strategies for filariasis control show promise for integrated schistosomiasis and nematode infection programs. Successful integration requires identifying co-endemic areas and ensuring drug safety and program sustainability.
Area of Science:
- Public Health
- Infectious Diseases
- Parasitology
Context:
- Filariasis control relies on community-directed, decentralized drug distribution.
- This strategy is a potential model for integrated helminth control programs.
Purpose:
- To explore the feasibility of integrating filariasis, schistosomiasis, and intestinal nematode control programs.
- To identify prerequisites for successful program integration.
Summary:
- Community-directed interventions (CDI) for filariasis could be extended to control schistosomiasis and intestinal nematodes.
- Integration necessitates mapping co-endemic zones, defining target populations for ivermectin, albendazole, mebendazole, and praziquantel.
- Safety of combined drug administration and impact on healthcare systems and existing programs must be assessed.
Impact:
- Potential for highly cost-effective, integrated helminth control programs.
- Highlights the need for careful planning and safety assessments before program integration.
Related Concept Videos
01:15Anthelminthic Agents
Anthelmintic drugs differ significantly from antiparasitic therapies targeting protozoa, primarily due to differences in parasite biology. Whereas most protozoal treatments act on proliferating cells, anthelmintics are typically directed against mature, nonproliferative helminths. The therapeutic approach considers the helminth's reliance on neuromuscular coordination, glucose metabolism, and microtubular integrity for survival, reproduction, and localization within the host. Most anthelmintics...
01:22American Trypanosomiasis
Chagas disease, or American trypanosomiasis, is a vector-borne parasitic infection caused by Trypanosoma cruzi, a flagellated protozoan (kinetoplastid) of the family Trypanosomatidae. The disease is endemic in Latin America, although cases are increasingly reported worldwide due to human migration. Transmission most commonly occurs when feces of infected triatomine bugs contaminate bite wounds or mucosal surfaces; additional routes include congenital, transfusional, transplant-related, and oral...
01:30Leishmaniasis
Leishmaniasis is a protozoal disease caused by species of the genus Leishmania and transmitted through the bite of infected female sandflies. The parasite exists in two principal morphological forms during its life cycle. A sandfly acquires intracellular amastigotes from an infected reservoir host, such as a dog. Within the sandfly, these forms differentiate into motile, flagellated promastigotes. During a subsequent blood meal, promastigotes are injected into the human host, where they...
01:29Malaria
Malaria pathogenesis in humans reflects a delicate interplay between parasite biology and host response. Clinical illness reflects a host’s immune response to the parasite’s asexual replication cycle, which is often asymptomatic in individuals with partial immunity. From the parasite's perspective, transmission between mosquito and human with minimal host pathology is evolutionarily advantageous. Among the six Plasmodium species infecting humans, P. falciparum and P. vivax dominate in global...