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[Case with probable dementia with Lewy bodies, who shows reduplicative paramnesia and Capgras syndrome]

Kazuyuki Ohara1, Yoshio Morita

  • 1Department of Neuropsychiatry, Hyogo College of Medicine. ohara-k@hyo-med.ac.jp

Seishin Shinkeigaku Zasshi = Psychiatria Et Neurologia Japonica
|September 27, 2006
PubMed

Insights

This case study highlights reduplicative paramnesia and Capgras syndrome in probable dementia with Lewy bodies (DLB). These misidentification syndromes may stem from disrupted visuospacial recognition and recursive consciousness in DLB.

Area of Science:

  • Neuroscience
  • Neurology
  • Psychiatry

Background:

  • Dementia with Lewy bodies (DLB) is a common neurodegenerative disorder.
  • DLB is characterized by cognitive decline, visual hallucinations, and parkinsonism.
  • Misidentification syndromes, such as reduplicative paramnesia (RP) and Capgras syndrome (CS), are less commonly reported in DLB.

Observation:

  • A 60-year-old male with progressive dementia developed fluctuating cognitive impairment and visual hallucinations.
  • SPECT imaging revealed hypoperfusion in the parieto-occipital lobes, predominantly in the right hemisphere.
  • The patient exhibited self- and other-transfiguration, consciousness of non-existent entities, and fluctuating visuospatial impairment, culminating in RP and CS.

Findings:

  • The patient was diagnosed with probable DLB based on clinical presentation and neuroimaging.
  • RP and CS in this case were linked to a sense of transfiguration, misidentification, and productive symptoms like visual hallucinations.
  • These symptoms may arise from impaired visuospacial recognition and disturbed recursive consciousness due to Lewy body pathology.

Implications:

  • This case expands the understanding of the neuropsychiatric manifestations of DLB.
  • It suggests a potential link between parieto-occipital dysfunction and complex misidentification syndromes in DLB.
  • Further research is needed to elucidate the neural mechanisms underlying these phenomena in DLB.

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