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Related Experiment Video

Updated: Jul 9, 2026

An Ivor Lewis Esophagectomy Designed to Minimize Anastomotic Complications and Optimize Conduit Function
09:40

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Published on: April 17, 2020

Transhiatal esophagectomy (THE).

Maria Letizia Vita1, Alessio Piraino, Adele Tessitore

  • 1Dipartimento di Chirurgia Toracica, UniversitĂ  Cattolica del S. Cuore, Policlinico A.Gemelli, Roma, Italy. marialetiziavita@yahoo.it

Rays
|September 27, 2006
PubMed
Summary

Transhiatal esophagectomy (THE) offers lower morbidity than transthoracic approaches. Despite concerns about lymphadenectomy, THE is a viable option for esophageal cancer, with outcomes comparable to other methods.

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Area of Science:

  • Surgical Oncology
  • Gastrointestinal Surgery
  • Esophageal Cancer Treatment

Background:

  • Transhiatal esophagectomy (THE) is a surgical technique for esophageal removal without thoracotomy.
  • It involves abdominal and cervical approaches, pioneered by Orringer with extensive experience.
  • THE is associated with lower morbidity compared to transthoracic esophagectomy.

Purpose of the Study:

  • To evaluate the suitability of Transhiatal Esophagectomy (THE) for esophageal cancer.
  • To compare the outcomes of THE with transthoracic approaches for esophageal cancer treatment.
  • To analyze the role of surgical technique versus tumor biology in esophageal cancer prognosis.

Main Methods:

  • Review of Transhiatal Esophagectomy (THE) technique and its application in esophageal cancer.
  • Comparison of morbidity and survival data between THE and transthoracic esophagectomy.
  • Analysis of factors influencing esophageal carcinoma outcomes, including tumor stage and systemic disease.

Main Results:

  • THE demonstrates lower morbidity than transthoracic approaches.
  • Controversy exists regarding THE's suitability for cancer due to lack of en-bloc lymphadenectomy.
  • No significant statistical differences in overall outcomes were observed between THE and transthoracic approaches for esophageal cancer.

Conclusions:

  • Transhiatal Esophagectomy (THE) is a viable surgical option for esophageal cancer, offering reduced morbidity.
  • Tumor biology and stage are critical determinants of esophageal cancer prognosis, often outweighing surgical technique.
  • Further research may clarify the role of lymphadenectomy in THE for specific cancer presentations.