Related Experiment Video
Updated: Feb 8, 2026

Measuring Statistical Learning Across Modalities and Domains in School-Aged Children Via an Online Platform and Neuroimaging Techniques
Published on: June 30, 2020
Appendicitis in children younger than 3 years of age: an 18-year experience
Yu-Tang Chang1, Jan-You Lin, Yu-Sheng Huang
1Division of Pediatric Surgery, Department of Surgery, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.
Insights
Appendicitis in children under 3 is concerning due to perforation risks. Delayed diagnosis in these young patients leads to longer hospital stays and more complications, emphasizing the need for earlier intervention.
Area of Science:
- Pediatric Surgery
- Gastroenterology
Background:
- Appendicitis in children under 3 years old presents diagnostic challenges.
- It is associated with a high rate of perforation.
Purpose of the Study:
- To analyze the experience with appendicitis in children younger than 3 years.
- To evaluate factors contributing to delayed diagnosis and subsequent outcomes.
Main Methods:
- Retrospective analysis of nine children under 3 years diagnosed with appendicitis over 18 years.
- Comparison of outcomes between patients presenting within 48 hours versus those presenting after 48 hours.
Main Results:
- All nine children presented with perforated appendicitis.
- Patients with delayed presentation (>48 hours) were younger, had higher C-reactive protein, and experienced longer operation times, postoperative ileus, and length of hospital stay (LOS).
- Seven patients had complications, including anemia and wound infections.
Conclusions:
- Delayed diagnosis is common in young children with appendicitis.
- Fever, diarrhea, and abdominal distention may indicate late-stage perforation.
- Earlier surgical intervention could potentially reduce prolonged LOS, operation time, and postoperative complications.
Abstract:
Appendicitis in children younger than 3 years of age has always been of concern due to its low incidence and high perforation rate. In this study, we analyzed our experience and evaluated the factors contributing to the delay in diagnosis. During the last 18 years, there were nine children younger than 3 years of age who presented with appendicitis. Four of these patients visited our emergency department within 48 hours after the onset of symptoms, while the symptoms had already persisted for more than 48 hours in the remaining five patients before their arrival in our emergency department. Perforated appendicitis was found in all children. Once the perforation had occurred for more than 2 days, complaints of fever, abdominal distention, and diarrhea were common. Compared to patients with symptoms for less than 2 days, those with symptoms for more than 2 days were younger and had higher serum C-reactive protein levels, significantly longer operation time, duration of postoperative ileus and length of hospital stay (LOS) (p = 0.026, 0.014, 0.018, and 0.014, respectively). No mortality was noted in the entire series, but seven of the nine patients had one or more complications, which may have prolonged LOS; anemia and wound infections were the two most common problems. Since delayed diagnosis is common, a thorough understanding of the clinical course of perforated appendicitis is important. Fever, diarrhea, and abdominal distention seem to be late manifestations. Prolonged LOS, operation time, and postoperative complications may be reduced if the operation is performed earlier.
More Related Videos
Related Concept Videos
Appendicitis-I: Introduction
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
Appendicitis-II: Diagnostic Studies and Management
Diagnosing Appendicitis
It requires a multifaceted approach, starting with a detailed physical examination to pinpoint the location and nature of the pain and identify any associated symptoms. Laboratory tests play a crucial role. A complete Blood Count (CBC) typically reveals leukocytosis (an increased number of...
Aging
Cellular Clock Theory
The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...
What is an Experiment?
The Effect of Aging on Tissues
Thomson's e/m Experiment
A particle with charge q, speed v, and mass m enters an area from the top, where the magnetic and electric fields are perpendicular both to the particle's motion and to one another. The magnetic...

