Comparison of primary wound closure versus open wound management in perforated appendicitis
Ruey-An Chiang1, Shan-Long Chen, Yao-Chung Tsai
1Department of Surgery, Mackay Memorial Hospital, Taitung Branch, No. 1 Lane 303 Chang-Sha Street, Taitung 950, Taiwan. ryan@ttms.mmh.org.tw
Insights
For perforated appendicitis, open wound management is preferable to primary closure in adults. This approach leads to a lower incidence of surgical wound infection (SWI) and shorter hospital stays.
Area of Science:
- General Surgery
- Infectious Disease
Background:
- Open wound management is standard for perforated appendicitis.
- Primary closure is a newer approach aiming to reduce costs and morbidity.
Purpose of the Study:
- Compare open wound management versus primary closure for perforated appendicitis in adults.
- Evaluate outcomes including surgical wound infection (SWI) and length of stay (LOS).
Main Methods:
- Retrospective review of 65 adult patients with perforated appendicitis.
- Comparison of outcomes between primary wound closure (41 patients) and open wound management (24 patients).
Main Results:
- Primary closure resulted in a significantly higher SWI rate (43.9% vs. 4.2%, p < 0.001).
- Patients with primary closure had a longer LOS (10 days vs. 7.9 days, p = 0.044).
- Readmission rates were higher with primary closure but not statistically significant.
Conclusions:
- Open wound management appears superior for perforated appendicitis in adults.
- Lower SWI rates and shorter LOS favor open wound management.
- Further randomized trials are necessary to confirm these findings.
Background/Purpose:
Open wound management has long been the most common practice after appendectomy for perforated appendicitis. Primary closure, however, has recently been advocated to reduce cost and morbidity. The aim of this study was to compare the results of open wound management and primary wound closure in adult patients (age, > or =15 years) with perforated appendicitis.
Methods:
Hospital records of 390 patients (age, > or =15 years) who underwent appendectomy between January 2002 and December 2004 were reviewed to identify surgical wound infection (SWI) and pathologic diagnosis. Perforated appendicitis was the indication for appendectomy in 65 of these patients. The incision wounds in these 65 patients were closed primarily in 41 and left open at the end of the operation in 24. The duration of symptoms, white blood cell count, operative time, incidence of SWI, length of stay (LOS) and readmission rate were compared between patients with these two different methods of wound management.
Results:
Patients whose wounds were closed primarily had a higher incidence of SWI (43.9% vs. 4.2%, p < 0.001) and longer LOS (10 days vs. 7.9 days, p = 0.044). The readmission rate was also higher for patients whose wounds were closed primarily; however, this difference was not significant.
Conclusion:
Open wound management may be preferable to primary wound closure for perforated appendicitis in adults because of a lower incidence of SWI and a shorter LOS. Randomized clinical trials, however, are needed to establish these findings.
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