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Diabetic foot disease.

Nidal A Younes1, Azmi T Ahmad

  • 1Department of Surgery, University of Jordan, Amman, Jordan.

Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists
|September 28, 2006
PubMed
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Diabetic foot disease (DFD) encompasses a range of issues caused by neuropathy and poor circulation. Effective management requires regular care, glucose control, and prompt treatment to prevent amputation.

Area of Science:

  • Podiatry
  • Endocrinology
  • Vascular Surgery

Background:

  • Diabetic foot disease (DFD) is a significant complication of diabetes mellitus.
  • It presents with diverse etiologies, including neuropathy, vascular insufficiency, and foot deformities.
  • DFD encompasses a spectrum from minor skin lesions to severe gangrene requiring amputation.

Purpose of the Study:

  • To review the spectrum of diabetic foot disease (DFD).
  • To identify the underlying etiologic factors contributing to DFD.
  • To outline the clinical evaluation, severity, and management strategies for DFD.

Main Methods:

  • A comprehensive review of existing literature on diabetic foot disease.
  • Discussion of relevant foot anatomy and pathophysiology.

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  • Outline of clinical evaluation, severity assessment, and management principles.

    • Main Results:

    • DFD is associated with neuropathy, vascular insufficiency, and bone deformities.
    • Pathologic forms range from skin lesions and infections to necrosis and gangrene.
    • Clinical severity varies widely, with a risk of amputation in severe cases.

    Conclusions:

    • Optimal DFD management requires a multimodal approach.
    • Key elements include regular foot care, glycemic control, and early problem recognition.
    • Surgical intervention, antibiotics, and off-loading are crucial for preventing progression.