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Updated: Jul 19, 2026

Spontaneous Murine Model of Anaplastic Thyroid Cancer
Published on: February 3, 2023
Cancer in the thyroid is not always thyroid cancer
Katherine E Akester1, Noel Somasundaram, Salvador Diaz-Cano
1Department of Endocrinology, St. Bartholomew's Hospital, London EC1A 7BE, UK.
Abstract:
Most clinicians assume that a thyroid mass which appears to be malignant is most likely a tumour arising from thyroid cells. We present a case where the thyroid malignancy was associated with a degree of systemic clinical and biochemical disturbance which suggested alternative diagnoses, and in which fine-needle aspiration revealed that the patient had a thyroid lymphoma. Gastric biopsy showed that this was a primary gastric diffuse B cell lymphoma. Subsequent management provided a number of challenging and overlapping problems, and the patient eventually died from this high-grade malignancy. We review the prevalence, presentation, diagnosis and management of lymphomas presenting as thyroid masses, and underline the problems in management when there is multi-system disease.
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