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Effects of glucose-dependent insulinotropic peptide on osteoclast function

Qing Zhong1, Takashi Itokawa, Supriya Sridhar

  • 1Institute of Molecular Medicine and Genetics, Medical College of Georgia, Augusta, GA 30912, USA.

American Journal of Physiology. Endocrinology and Metabolism
|September 28, 2006
PubMed
Summary

Nutrient intake rapidly reduces bone breakdown. Glucose-dependent insulinotropic peptide (GIP) directly inhibits osteoclast activity, explaining this post-meal bone resorption reduction.

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