Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Frontal lobe atrophy after prolonged frontal bone defect.

Daniel Marchac1, Dominique Renier, Eric Arnaud

  • 1Craniofacial Group, Paris, France. danielmarchac@hotmail.com

The Journal of Craniofacial Surgery
|September 28, 2006
PubMed
Summary

A delayed frontal bone reconstruction after infection in a Crouzon syndrome patient led to frontal lobe atrophy. This resulted in significant psychological and behavioral issues due to prolonged microtrauma.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Respiratory and craniofacial management in children with Apert syndrome.

Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery·2025
Same author

Craniosynostosis as a cause of intracranial hypertension in Alagille syndrome: a case series of 6 consecutive pediatric patients.

Neurosurgical focus·2025
Same author

Differences in Scalp Tension Associated With Craniosynostosis Among Patients of Different Races.

The Journal of craniofacial surgery·2024
Same author

Regulatory elements in <i>SEM1-DLX5-DLX6</i> (7q21.3) locus contribute to genetic control of coronal nonsyndromic craniosynostosis and bone density-related traits.

Genetics in medicine open·2024
Same author

Frontal Bone Resorption after Frontofacial Monobloc Advancement in FGFR -Related Craniosynostoses: Predictive Factors.

Plastic and reconstructive surgery·2024
Same author

AI-based diagnosis and phenotype - Genotype correlations in syndromic craniosynostoses.

Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery·2024

Area of Science:

  • Neurosurgery
  • Craniofacial Surgery
  • Pediatric Plastic Surgery

Background:

  • Crouzon syndrome is a craniosynostosis disorder requiring surgical intervention.
  • Monobloc advancement is a surgical technique used to correct craniofacial deformities.
  • Infection leading to frontal bone loss is a known complication of monobloc advancement.

Observation:

  • A 12-year-old Crouzon patient lost frontal bone due to infection post-monobloc advancement.
  • The patient was lost to follow-up for nine years before seeking reconstruction.
  • Reconstruction with a titanium plate was initially satisfactory.

Findings:

  • The patient developed significant frontal lobe atrophy.
  • The atrophy is hypothesized to result from long-term frontal bone absence and microtrauma.

Related Experiment Videos

  • The patient exhibited behavioral changes consistent with frontal lobotomy.

    • Implications:

    • Prolonged absence of frontal bone reconstruction can lead to severe neurological sequelae.
    • Early repair of frontal bone defects is crucial to prevent secondary complications.
    • This case highlights the importance of consistent follow-up in pediatric craniofacial surgery.