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Updated: Jul 19, 2026
A Mouse Model of Single and Repetitive Mild Traumatic Brain Injury
Published on: June 20, 2017
[Mild brain injuries: definition, classifications and prognosis]
1Service de Chirurgie Maxillo-faciale et Stomatologie, CHU de Besançon, France. chir-maxi-fac@chu-besancon.fr
Abstract:
Brain injuries may be graded into mild, moderate and severe depending on clinical and radiological criterions. Mild brain injuries (MBI) are usually defined by an initial unconsciousness limited to 30 minutes, a Glasgow score between 13 and 15, the absence of intra-cranial lesion on the CT scan, a post-traumatic amnesia period between one and 24 hours depending on the authors. The consequences of a MBI may be simple but the injured often suffer from a transitory post-concussive syndrome. Traumatic stress states are a well known pathology and consist in a psychological reaction against the trauma. The acute traumatic stress may or may not run its course to a chronic post-traumatic stress disorder, formerly called post-traumatic neurosis.
Insights
Mild brain injuries (MBI) can lead to post-concussive syndrome, a common consequence. Acute traumatic stress may develop into chronic post-traumatic stress disorder.
Area of Science:
- Neurology
- Psychiatry
Context:
- Brain injuries are classified as mild, moderate, or severe based on clinical and radiological findings.
- Mild brain injuries (MBI) are characterized by specific diagnostic criteria.
Purpose:
- To define the criteria for mild brain injuries (MBI).
- To describe the potential consequences of MBI, including post-concussive syndrome and traumatic stress.
- To differentiate between acute traumatic stress and chronic post-traumatic stress disorder.
Summary:
- Mild brain injuries (MBI) are diagnosed using criteria such as limited unconsciousness (≤30 minutes), Glasgow Coma Scale scores (13-15), normal CT scans, and post-traumatic amnesia (1-24 hours).
- Common sequelae of MBI include transient post-concussive syndrome.
- Psychological reactions to trauma, such as acute traumatic stress, can evolve into chronic post-traumatic stress disorder.
Impact:
- Understanding MBI criteria aids in accurate diagnosis and patient stratification.
- Recognizing the potential for post-concussive syndrome and PTSD is crucial for effective patient management and treatment.
- This information supports clinical decision-making and research into brain injury outcomes.
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