Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

A guide for diagnostic evaluations.

Rosanna W Peeling1, Peter G Smith, Patrick M M Bossuyt

  • 1UNICEF/UNDP/ World Bank/WHO Special Programme for Research & Training in Tropical Diseases (TDR), World Health Organization, 20 Avenue Appia, CH-1211 Geneva 27, Switzerland. peelingr@who.int

Nature Reviews. Microbiology
|September 28, 2006
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Incidence of Cancer in Patients With Familial Adenomatous Polyposis in the Netherlands: A Nationwide Cohort Study.

Gastroenterology·2026
Same author

QUADAS-3 Explanation and Elaboration: Guidance for Quality Assessment of Diagnostic Test Accuracy Studies.

Annals of internal medicine·2026
Same author

QUADAS-3: A Revised Tool for the Quality Assessment of Diagnostic Test Accuracy Studies.

Annals of internal medicine·2026
Same author

Risk factors for dysplastic lesions in the proximal stomach in patients with familial adenomatous polyposis.

Endoscopy international open·2025
Same author

Rationale and design of 'StAtins in Frail oldEr patients with ischemic Stroke or Transient ischemic attack-the Randomized Controlled Trial' (SAFEST-RCT).

BMJ neurology open·2025
Same author

Quantitative targeted proteomics for occult cancer screening in patients with unprovoked venous thromboembolism: results from the prospective PLATO-VTE study.

Research and practice in thrombosis and haemostasis·2025
Same journal

Waterborne diseases and climate change.

Nature reviews. Microbiology·2026
Same journal

Climate adaptation and biodiversity shape West Nile virus risk in cities.

Nature reviews. Microbiology·2026
Same journal

Climate factors and evolution drive cholera surges in Dhaka.

Nature reviews. Microbiology·2026
Same journal

Climate change boosts Salmonella antimicrobial resistance.

Nature reviews. Microbiology·2026
Same journal

Reframing risk assessment for malaria elimination in a changing climate.

Nature reviews. Microbiology·2026
Same journal

Bacterial vesicles protect the membrane during polymyxin stress.

Nature reviews. Microbiology·2026
See all related articles

Diagnostic test quality is poor in developing nations due to weak regulations. This leads to inaccurate results, misdiagnosis, and ineffective patient care, hindering infectious disease control.

Area of Science:

  • Medical Diagnostics
  • Infectious Disease Control
  • Public Health Policy

Background:

  • Accurate diagnostic tests are crucial for managing infectious diseases and patient care.
  • Developing countries often lack regulatory oversight for diagnostic test quality.
  • Substandard diagnostic tests compromise clinical care and disease control efforts.

Purpose of the Study:

  • To highlight the critical role of accurate diagnostic tests in healthcare.
  • To address the challenges posed by poor quality diagnostic tests in developing countries.
  • To emphasize the need for improved regulatory controls and evidence-based test selection.

Main Methods:

  • The study reviews the impact of diagnostic test performance on patient management.
  • It examines the consequences of inadequate study designs in evaluating test characteristics.

Related Experiment Videos

  • The analysis focuses on the availability and use of diagnostic tests without proven effectiveness.

    • Main Results:

    • Diagnostic test quality is frequently compromised in developing countries due to insufficient regulatory frameworks.
    • Studies assessing test performance often suffer from design flaws, leading to biased or unreliable data.
    • Consequently, diagnostic tests are widely used without validated evidence of their effectiveness.

    Conclusions:

    • The lack of regulatory control over diagnostic tests in developing nations leads to significant public health challenges.
    • Misdiagnosis resulting from unreliable tests causes treatment failures and resource wastage.
    • Strengthening regulatory systems and ensuring evidence-based procurement are essential for improving healthcare outcomes.