The cannabinoid receptor: biochemical, anatomical and behavioral characterization
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A C Howlett1, M Bidaut-Russell, W A Devane
1Department of Pharmacology, St Louis University School of Medicine, MO 63104.
Trends in Neurosciences
|October 1, 1990
Abstract:
The actions of the active principle of marihuana, delta 9-tetrahydrocannabinol, are mimicked by synthetic cannabinoid agonists showing high potency and enantio-selectivity in behavioral assays. These drugs have been used to characterize cannabinoid receptor binding, biochemistry and pharmacology, leading to a better understanding of the effects of cannabinoids in the CNS of humans and experimental animals.