Related Experiment Video

Updated: Jul 19, 2026

Modeling Stroke in Mice: Transient Middle Cerebral Artery Occlusion via the External Carotid Artery
07:26

Modeling Stroke in Mice: Transient Middle Cerebral Artery Occlusion via the External Carotid Artery

Published on: May 24, 2021

Many hypotheses but no replication for the association between PDE4D and stroke

Jonathan Rosand, Nick Bayley, Natalia Rost

    Nature Genetics
    |September 29, 2006
    PubMed
    Summary

    No abstract available in PubMed .

    More Related Videos

    A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia
    06:01

    A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia

    Published on: August 18, 2015

    Related Experiment Videos

    Last Updated: Jul 19, 2026

    Modeling Stroke in Mice: Transient Middle Cerebral Artery Occlusion via the External Carotid Artery
    07:26

    Modeling Stroke in Mice: Transient Middle Cerebral Artery Occlusion via the External Carotid Artery

    Published on: May 24, 2021

    A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia
    06:01

    A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia

    Published on: August 18, 2015

    Related Concept Videos

    Treatment for Pulmonary Arterial Hypertension: Phosphodiesterase Inhibitors01:28

    Treatment for Pulmonary Arterial Hypertension: Phosphodiesterase Inhibitors

    Phosphodiesterase 5 (PDE5) inhibitors are potent enzymes that function to hydrolyze cyclic nucleotides to their corresponding 5' monophosphates. Their unique biochemical properties have been applied in treating Pulmonary Arterial Hypertension (PAH).
    Among the PDE5 inhibitors, sildenafil (Revatio) stands out as a competitive and selective inhibitor. It operates by elevating cellular levels of cGMP and augmenting signaling through the cGMP-PKG pathway, promoting vasodilation. Upon oral...
    Ischemic Stroke ll: Pathophysiology01:15

    Ischemic Stroke ll: Pathophysiology

    An ischemic stroke occurs when a cerebral blood vessel becomes obstructed, most often by a thrombus or embolus, interrupting the delivery of oxygen and glucose to brain tissue. Because neurons rely on continuous aerobic metabolism, energy failure begins within minutes of reduced perfusion. The region receiving the least blood flow becomes the infarct core, an area of irreversible cellular death. Surrounding this core lies the penumbra, a zone of hypoperfused but still viable tissue that is...

    Articles linked to this work by shared authors, journal, and citation graph.

    Association of Leucocyte Telomere Length With Stroke, Dementia, and Late-Life Depression: The Role of Modifiable Risk Factors.

    Neurology·2025

    Associations Between Trust in Healthcare Professionals and Perceptions of Modifiability of Dementia and Stroke Risks Through Maintaining or Changing Lifestyle Habits.

    American journal of health promotion : AJHP·2025

    The Brain Care Score and its associations with cardiovascular disease and cancer.

    Family practice·2025

    Harvard Electroencephalography Database: A comprehensive clinical electroencephalographic resource from four Boston hospitals.

    Epilepsia·2025

    The Harvard-Emory ECG Database.

    medRxiv : the preprint server for health sciences·2025

    Use of the Brain Care Score to Estimate the Risk of Incident Cerebrovascular Events in Middle-Aged Women.

    Neurology·2025

    High-resolution promoter interaction analysis implicates genes involved in activation of type 3 innate lymphoid cells in immune disease risk.

    Nature genetics·2026

    Mapping enhancer-gene regulatory interactions from single-cell data.

    Nature genetics·2026

    Diversity and evolution of chromatin regulatory states across eukaryotes.

    Nature genetics·2026

    Gene mutant dosage is associated with prognosis and metastatic tropism in 60,000 clinical cancer samples.

    Nature genetics·2026

    Cumulative transcription factor binding and p300-mediated histone acetylation drive enhancer activation frequency.

    Nature genetics·2026

    Single-cell spatial mapping of human kidney development implicates the microenvironment in guiding cell fate decisions.

    Nature genetics·2026

    Post-COVID-19 pure red cell aplasia: A case report and literature review.

    SAGE open medical case reports·2026

    HBV RNA, HBcrAg, and HBsAg levels at year 6 do not predict HCC risk in patients with cirrhosis on long-term entecavir therapy.

    Hepatology international·2026

    Training and referral patterns for hypertension in the UK: huge demand for an untrained work force.

    The British journal of cardiology·2026

    Limited Interchangeability of Shunt-Side SpO2 Measurements During Hemodialysis.

    Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy·2026

    Non-O blood groups as independent predictors of chronic subdural hematoma recurrence in antithrombotic-naive patients: risk mitigation by prior aspirin use and new perspectives for stratification.

    Journal of neurosurgery·2026

    Effect of anaesthesia modality on outcome in medium or distal vessel occlusion stroke: a post-hoc analysis of the DISTAL trial.

    European stroke journal·2026
    See all related articles
    JoVE
    x logofacebook logolinkedin logoyoutube logo
    ABOUT JoVE
    OverviewLeadershipBlogJoVE Help Center
    AUTHORS
    Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
    LIBRARIANS
    TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
    RESEARCH
    JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
    EDUCATION
    JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
    Terms & Conditions of Use
    Privacy Policy
    Policies
    Jove
    Visualize
    Contact Us