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[A 54-year-old man with a large subcutaneous skull erosion and focal epileptic seizures]

Anne Vik1, Anne Kvikstad, Geirmund Unsgård

  • 1Nevrokirurgisk avdeling, St. Olavs Hospital, 7006 Trondheim. anne.vik@ntnu.no

Tidsskrift for Den Norske Laegeforening : Tidsskrift for Praktisk Medicin, Ny Raekke
|September 30, 2006
PubMed
Abstract

Insights

Extracranial metastases from meningioma are rare but can occur. This case highlights a patient with atypical meningioma who developed lung and pleural metastases years after initial treatment, emphasizing potential risk factors.

Area of Science:

  • Neuro-oncology
  • Pathology
  • Surgical Oncology

Background:

  • Extracranial metastases from meningioma are exceptionally rare, with an incidence below 0.1%.
  • Meningiomas are typically benign tumors arising from meningeal cells.

Observation:

  • A 54-year-old male presented with a parasagittal meningioma causing skull erosion and soft tissue invasion.
  • The tumor invaded the superior sagittal sinus, necessitating postoperative radiation therapy.
  • Histological analysis confirmed an atypical meningioma.

Findings:

  • The patient experienced a recurrence 3.5 years post-surgery, followed by the detection of multiple lung and pleural tumors one year later.
  • Biopsy confirmed these secondary tumors as metastases with identical histology to the primary meningioma.
  • Risk factors for meningioma metastasis may include histological grade, venous sinus invasion, and local recurrence.

Implications:

  • This case underscores the potential for rare extracranial spread of atypical meningiomas.
  • Identifying and managing risk factors like venous sinus invasion is crucial for patient outcomes.
  • Further research into the metastatic potential of meningiomas is warranted.

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