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Alternative Cultures for Human Pluripotent Stem Cell Production, Maintenance, and Genetic Analysis
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Human embryonic stem cell culture: current limitations and novel strategies

N Findikli1, N Z Candan, S Kahraman

  • 1Istanbul Memorial Hospital ART and Reproductive Genetics Centre, Istanbul, Turkey. necatif@gmail.com

Reproductive Biomedicine Online
|September 30, 2006
PubMed

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Stem cell research aims to find ways to use stem cells to regenerate and repair cellular damage. Over time, most adult cells undergo the wear and tear of aging and lose their ability to divide and repair themselves. Stem cells do not display a particular morphology or function. Adult stem cells, which exist as a small subset of cells in most tissues, keep dividing and can differentiate into a number of specialized cells generally formed by that tissue. These cells enable the body to renew and...
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Stem cells are undifferentiated cells that divide and produce different cell types. Ordinarily, cells that have differentiated into a specific cell type are terminally differentiated; however, scientists have found a way to reprogram these mature cells so that they dedifferentiate and return to an unspecialized, proliferative state. These cells are pluripotent like embryonic stem cells—able to produce all cell types—and are called induced pluripotent stem cells (iPSCs).
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