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Intraperitoneal therapy for ovarian cancer: a treatment ready for prime time

Deborah K Armstrong1, Mark F Brady

  • 1Johns Hopkins Kimmel Cancer Center, Baltimore, MD, USA.

Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology
|September 30, 2006
PubMed
Abstract

No abstract available in PubMed .

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Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
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