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Updated: Jul 19, 2026

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
Published on: February 26, 2013
The modern surgical management of atrial fibrillation
Anil K Gehi1, David H Adams, Farzan Filsoufi
1Department of Cardiothoracic Surgery, Box 1028, Mount Sinai Medical Center, One East 100th Street, New York, NY 10029-6574, USA.
Insights
Surgical management of atrial fibrillation has advanced, with modified maze procedures showing excellent long-term efficacy. These simplified procedures should be considered for cardiac surgery patients with atrial fibrillation.
Area of Science:
- Cardiology
- Cardiac Surgery
Background:
- Atrial fibrillation (AF) is a common arrhythmia, particularly in valvular heart disease patients.
- AF significantly increases stroke risk (6-fold) and mortality (2-fold).
- Current medical management for AF rhythm control is suboptimal.
Observation:
- Surgical management of AF has seen significant innovation.
- The Cox-maze III procedure is the established surgical standard.
- Modifications and new energy sources have led to simplified maze procedures.
Findings:
- Simplified left-sided maze procedures demonstrate excellent intermediate and long-term efficacy.
- These modified procedures offer an effective alternative to traditional methods.
Implications:
- Modified maze procedures should be offered to mitral valve surgery patients.
- Consideration should be given to offering these procedures to all cardiac surgery patients with AF.
Abstract:
Atrial fibrillation is the most common arrhythmia disorder. Its incidence is especially high among patients with valvular heart disease. Patients with atrial fibrillation are at a six-fold increased risk of stroke and a two-fold increased risk of mortality. Medical management for rhythm control of patients with atrial fibrillation is suboptimal and no better than simple rate management. However, catheter-based therapies are undergoing intense development. The surgical management of atrial fibrillation has undergone considerable innovation in the last two decades; it is the subject of this review. The "cut-and-sew" Cox-maze III is considered the standard for surgical therapy for atrial fibrillation. More recently, several modifications of the Cox maze lesion set and the development of alternative energy sources to achieve transmural atrial lesions have led to a more simplified maze procedure. This simplified left-sided maze procedure has demonstrated excellent efficacy at intermediate and long-term follow-up. Therefore, the modified maze procedure should be offered to all mitral valve surgery patients and potentially to all cardiac surgery patients with a history of paroxysmal, persistent, or permanent atrial fibrillation.
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