Related Experiment Video
Updated: Jul 19, 2026

Therapeutic Massage for Psychological Well-being in Geriatric Oncology
Published on: May 22, 2026
Change in psychological resources of younger and older cancer patients during chemotherapy
Martin Pinquart1, Cornelia Fröhlich, Rainer K Silbereisen
1Department of Developmental Psychology and Center for Applied Developmental Science, Friedrich Schiller University, Jena, Germany. Martin.Pinquart@uni-jena.de
Abstract:
Psychological resources were investigated in 150 recently diagnosed adult cancer patients and in 150 healthy control group members. Before the start of chemotherapy, cancer patients reported higher levels of optimism, purpose in life than their healthy peers, and self-esteem (only younger patients) whereas no between-group differences emerged for internal locus of control. However, the mobilization of psychological resources was limited to younger patients, and varied by item content. Over a 9-month period, most psychological resources of cancer patients showed a small but significant decline, and patients with higher illness-related stressors (e.g. stronger functional impairments, low perceived success of therapy) were more likely to decline in resources. We conclude that in line with cognitive adaptation theory cancer diagnosis leads to an initial mobilization of psychological resources in younger patients, but that over the course of therapy psychological resources decline to a level that would be expected in healthy adults.
Related Concept Videos
Pharmacodynamics in Geriatric Patients: Effects of Age
Cancer Therapies
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
Cancer Therapies
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
Drug Dosing: Geriatric Patients
Psychoneuroimmunology: Diabetes and Cancer
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption