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Updated: Jul 19, 2026

The Synthesis of RGD-functionalized Hydrogels as a Tool for Therapeutic Applications
Published on: October 7, 2016
Synthesis of well-defined hydrogel networks using click chemistry
Michael Malkoch1, Robert Vestberg, Nalini Gupta
1Materials Research Laboratory, University of California, Santa Barbara, California 93106, USA.
Abstract:
New PEG-based hydrogel materials have been synthesized by Click chemistry and shown to result in well-defined networks having significantly improved mechanical properties; the selectivity of the azide/acetylene coupling reaction also allows for the incorporation of various additives and functional groups leading to chemical tailoring of the hydrogels.
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