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Related Concept Videos

Tumor Immunotherapy01:27

Tumor Immunotherapy

Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
Cancer Vaccines01:30

Cancer Vaccines

Cancer treatment vaccines are a rapidly evolving field that offers a promising approach to immunotherapy. Unlike traditional vaccines that prevent diseases, cancer treatment vaccines are designed to treat existing cancers by stimulating the immune system to recognize and attack cancer cells.
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
Cancer Therapies02:49

Cancer Therapies

Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
Cancer Therapies02:49

Cancer Therapies

Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
Targeted Cancer Therapies02:57

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against specific...
Targeted Cancer Therapies02:57

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against specific...

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Related Experiment Video

Updated: Jul 19, 2026

Paramyxoviruses for Tumor-targeted Immunomodulation: Design and Evaluation Ex Vivo
12:42

Paramyxoviruses for Tumor-targeted Immunomodulation: Design and Evaluation Ex Vivo

Published on: January 7, 2019

Vaccination therapy in malignant disease.

M M Aloysius1, R A Robins, J M Eremin

  • 1Section of Surgery, Nottingham University Hospitals, Queen's Medical Centre, UK. mark.aloysius@nottingham.ac.uk

The Surgeon : Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland
|October 3, 2006
PubMed
Summary

Anti-cancer immunotherapy shows promise for advanced cancers, offering a new strategy where traditional treatments fall short. This review explores the immune system

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Area of Science:

  • Oncology
  • Immunology
  • Cancer Research

Background:

  • Survival rates for early-stage cancers have improved, but advanced malignancy remains a significant clinical challenge.
  • Current therapeutic strategies for advanced cancers have limited impact on long-term survival.
  • Anti-cancer immunotherapy presents a novel and experimental therapeutic approach.

Purpose of the Study:

  • To review the fundamental immunological interactions between the host immune system and tumors.
  • To elucidate the mechanisms of anti-tumor immune responses stimulated by immunotherapy.
  • To summarize key in vivo pilot studies of active specific immunotherapy in solid cancers over the past five years.

Main Methods:

  • Literature review focusing on immunological interplay in cancer.
  • Analysis of mechanisms underlying immunotherapy-induced anti-tumor responses.
  • Synthesis of findings from recent in vivo pilot studies in solid tumors.

Main Results:

  • Discussion of the complex host immune system-tumor interactions.
  • Explanation of how immunotherapy elicits anti-tumor immune responses.
  • Presentation of data from recent immunotherapy pilot studies in various solid cancers.

Conclusions:

  • Active specific immunotherapy offers a potential new therapeutic avenue for advanced malignancies.
  • Understanding the immune-tumor interplay is crucial for developing effective immunotherapies.
  • Recent pilot studies indicate the potential of immunotherapy in treating solid tumors.