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Updated: Aug 15, 2026
Lymphocyte Isolation from Human Skin for Phenotypic Analysis and Ex Vivo Cell Culture
Published on: April 8, 2016
CD1-positive epidermal Langerhans cells in regressed tuberculoid and lepromatous leprosy lesions
R B Narayanan1, A Girdhar, B K Girdhar
1Central JALMA Institute for Leprosy (ICMR), Agra, India.
Abstract:
A comparison was made of the numbers of epidermal Langerhans cells in active and regressed lesions of tuberculoid and lepromatous leprosy using the OKT6 and OKIa monoclonal antibodies. A reduction in the numbers of CD1+ epidermal Langerhans cells was noticed in the regressed lesions of both the tuberculoid and lepromatous leprosy lesions unlike the active lesions. The majority of infiltrates in both types of regressed lesions were HLA-DR+ and CD1-.
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