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Identifying Dysregulated Genes Induced by Kaposi's Sarcoma-associated Herpesvirus (KSHV)
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Published on: September 14, 2010

HIV and skin cancer

Kord S Honda1

  • 1Division of Dermatology, Box 356524, University of Washington School of Medicine, 1959 NE Pacific Street, Seattle, WA 98195, USA. kordhnda@u.washington.edu

Dermatologic Clinics
|October 3, 2006
PubMed

AIDS produces profound alterations in normal immunity. Impaired cellular immunity permits new tumor formation as evidenced by the solid-organ transplant literature. The weakened cellular immune system of HIV-infected patients resembles in some ways the iatrogenic immunosuppression in solid-organ transplant recipients. This article summarizes what is known about skin cancer in the solid-organ transplant population and compares the immunodysregulation of HIV infection with the iatrogenic immunosuppression following solid-organ transplantation.

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