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Common epitope on urinary antigen derived from different Legionella pneumophila serogroup 1 strains recognized by a
1Medical Academy Carl Gustav Carus Dresden, Institute of Medical Microbiology, GDR.
Zentralblatt Fur Bakteriologie : International Journal of Medical Microbiology
|September 1, 1990
Abstract:
Guinea pigs were infected intraperitoneally with 4 subgroup reference strains (Knoxville 1, Philadelphia 1, Bellingham 1, OLDA) and 2 clinical isolates of Legionella pneumophila serogroup 1. Antigenuria was demonstrated by the enzyme-linked immunosorbent assay using polyclonal antibodies and monoclonal antibody (mab) F8/5. Mab F8/5 recognizes a hitherto undetected common epitope on urinary antigen of the investigated strains.