Echocardiographic manifestations of Adamantiades-Behcet's disease

David Leibowitz1, David Planer, Tova Chajek-Shaul

  • 1Coronary Care Unit and Department of Medicine, Hadassah University Hospital, P.O. Box 24035 Mount Scopus, Jerusalem 91120, Israel. oleibo@hadassah.org.il

Insights

Adamantiades-Behcet disease (ABD) is a chronic inflammatory condition affecting multiple systems, including the cardiovascular system. Echocardiography is vital for assessing cardiovascular pathology in ABD patients, revealing diverse findings.

Area of Science:

  • Cardiology
  • Rheumatology
  • Internal Medicine

Background:

  • Adamantiades-Behcet disease (ABD) is a multisystemic, chronic inflammatory disorder of unknown cause.
  • While prevalent in the Mediterranean, Middle East, and Far East, ABD is increasingly seen in Western countries due to migration.
  • Cardiovascular manifestations are a significant concern in ABD.

Observation:

  • ABD can affect the myocardium, venous system, aorta, and great vessels.
  • Echocardiography plays a crucial role in diagnosing and monitoring cardiovascular involvement in ABD.
  • This review details the range of echocardiographic findings observed in ABD patients.

Findings:

  • Echocardiography can identify diverse cardiac pathologies associated with ABD.
  • Specific findings may include myocardial dysfunction, valvular abnormalities, and great vessel involvement.
  • The diagnostic utility of echocardiography in assessing ABD's cardiovascular impact is highlighted.

Implications:

  • Early and accurate echocardiographic assessment is crucial for managing cardiovascular complications in ABD.
  • Understanding the spectrum of echocardiographic findings aids in timely diagnosis and treatment strategies.
  • This review provides valuable insights for clinicians managing patients with Adamantiades-Behcet disease.

Related Concept Videos

Endocarditis II: Clinical Features of Infective Endocarditis01:25

Endocarditis II: Clinical Features of Infective Endocarditis

Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies01:22

Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies

The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...
Cardiomyopathy III: Hypertrophic Cardiomyopathy01:29

Cardiomyopathy III: Hypertrophic Cardiomyopathy

Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
Aortic Regurgitation II: Clinical Features and Diagnostic Tests01:22

Aortic Regurgitation II: Clinical Features and Diagnostic Tests

Aortic valve regurgitation (AR) occurs when the aortic valve fails to close properly, allowing blood to flow backward from the aorta into the left ventricle. This backflow can result in two distinct clinical presentations: acute and chronic AR, each characterized by its own set of symptoms and physical findings.Acute Aortic RegurgitationAcute AR presents with a sudden onset of severe symptoms. Patients typically experience profound dyspnea (shortness of breath), chest pain, and signs of left...
Imaging Studies for Cardiovascular System I:Echocardiography01:17

Imaging Studies for Cardiovascular System I:Echocardiography

Cardiac imaging studies encompass a wide range of noninvasive and minimally invasive techniques designed to visualize the heart's structure and function in detail. One such technique is echocardiography, which uses high-frequency ultrasound waves to produce detailed images of the heart, known as echocardiograms.
Indications: Echocardiography is utilized to diagnose heart failure, valve disorders, and myocardial infarction. It also assesses cardiac structures' size, shape, and motion, evaluates...
Hypertension III: Clinical Manifestations and Diagnostic Studies01:30

Hypertension III: Clinical Manifestations and Diagnostic Studies

Hypertension is asymptomatic and also referred to as the "silent killer" until it progresses to a severe stage or causes target organ disease. Patients may experience symptoms stemming from the strain on blood vessels and tissues in various organs or the heart's increased workload.Physical exams might show no abnormalities other than high blood pressure. Signs of vascular damage, when present, correspond to the organs supplied by the affected vessels, leading to target organ damage. For...