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Histologic effects of injection snoreplasty and radiofrequency in the rat soft palate
Ethem Poyrazoglu1, Salim Dogru, Bülent Saat
1Department of Otolaryngology, Haydarpasa Training Hospital, Turkey.
Objective:
This study was undertaken to compare the effects of radiofrequency and injection snoreplasty on the histological structure of the soft palate in an animal model.
Study Design And Setting:
This is a blinded, controlled histologic evaluation of rat soft palates that underwent separate palatal interventions. Fifty rats were divided into 5 groups of 10 rats (Group 1 = injection snoreplasty [IS], Group 2 = IS + steroid, Group 3 = saline injection, Group 4 = radiofrequency ablation [RFA], and Group 5 = no intervention). The animals were sacrificed after 24 hours, 1 week, 3 weeks, and 5 weeks. Then the soft palates were subjected to histological analysis.
Results:
Histological analysis demonstrated normal remucosalization in all specimens, with fibrosis increased in Group 1. Interstitial edema was minimal in Group 2. Keratinization was most apparent in Group 4.
Conclusion:
Radiofrequency and injection snoreplasty stiffen the rat soft palate compared with controls.
