Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Tissue-engineered trachea: History, problems and the future.

Qiang Tan1, Rudolf Steiner, Simon P Hoerstrup

  • 1Clinic of Thoracic Surgery, University Hospital Zurich, Zurich, Switzerland. tqiang@hotmail.com

European Journal of Cardio-Thoracic Surgery : Official Journal of the European Association for Cardio-Thoracic Surgery
|October 3, 2006
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Magnetically Repulsive Cushion Triboelectric Nanogenerator for Rotating Machinery Structural Health Monitoring.

Sensors (Basel, Switzerland)·2026
Same author

Spatially Decoupled Redox Activities Enable High Capacity and Fast Kinetics in Co-Free Li-Rich Cathodes.

ACS applied materials & interfaces·2026
Same author

[Predictors of Blood Transfusion after Allogeneic Hematopoietic Stem Cell Transplantation in Patients with Blood Diseases].

Zhongguo shi yan xue ye xue za zhi·2026
Same author

Gender Divergence in COPD Phenotypes and Narrowing Urban-Rural Diagnostic Gaps: A Surveillance Study in Chongqing, China, 2020-2024.

International journal of chronic obstructive pulmonary disease·2026
Same author

Fatty Liver Index as an Upstream Marker of Glycaemic and Cardiometabolic Dysregulation Preceding MASLD: Evidence From Two Longitudinal Cohorts.

Diabetes, obesity & metabolism·2026
Same author

Single-iron catalyst with heterogenized TEMPO for selective toluene electrooxidation to benzaldehyde at low potentials.

Nature communications·2026
Same journal

Mitral valve anomalies in transposition of the great arteries.

European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery·2026
Same journal

Oncologic Safety of Omitting Mediastinal Lymph Node Dissection in Segmentectomy for Ground-Glass Opacity-Dominant Lung Cancer: A Supplementary Analysis of JCOG1211.

European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery·2026
Same journal

Progress in Thymic Malignancy Care: The Imperative for Global Standards and Collaboration.

European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery·2026
Same journal

Association between interventional cardiologist practice characteristics, CABG use, and clinical outcomes.

European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery·2026
Same journal

The EACTS Innovation Committee's Perspective on the "Heart Valve of the Future".

European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery·2026
Same journal

Why Should the Current Generation of Surgical Residents be Academically Active-Lessons From the Past.

European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery·2026
See all related articles

This review summarizes 20 years of tissue-engineered trachea research, highlighting challenges and solutions. A novel

Area of Science:

  • Biomedical Engineering
  • Regenerative Medicine
  • Tissue Engineering

Background:

  • Significant advancements in tissue engineering over two decades.
  • Persistent technical challenges hinder complete trachea construction.
  • Research focus has evolved from cartilage to epithelial and vascular integration.

Purpose of the Study:

  • To review and synthesize 20 years of tissue-engineered trachea research.
  • To identify and address current technical bottlenecks in trachea regeneration.
  • To propose innovative solutions for overcoming existing limitations.

Main Methods:

  • Comprehensive literature review of tissue-engineered trachea studies.
  • Analysis of technical challenges and proposed solutions.

Related Experiment Videos

  • Conceptualization of a novel 'in vivo bioreactor' approach.

    • Main Results:

    • Identified key bottlenecks in scaffold fabrication, cell integration, and vascularization.
    • Documented a shift in research focus towards reepithelialization and revascularization.
    • Proposed the 'in vivo bioreactor' as a promising strategy for trachea engineering.

    Conclusions:

    • Overcoming reepithelialization and revascularization challenges is crucial for functional tissue-engineered tracheas.
    • The 'in vivo bioreactor' concept offers a potential breakthrough for scaffold perfusion and tissue integration.
    • Future research should focus on implementing and validating advanced bioreactor systems for trachea regeneration.