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Updated: Jul 19, 2026

Conjunctival Commensal Isolation and Identification in Mice
Published on: May 1, 2021
Bacterial culture isolates from hospitalized pediatric patients with conjunctivitis
Ahmad B Tarabishy1, Gerri S Hall, Gary W Procop
1Department of Internal Medicine, Cleveland Clinic Foundation, Cleveland, OH 44195, USA.
Insights
The most common bacteria causing acute bacterial conjunctivitis in hospitalized children were coagulase-negative Staphylococcus and viridans Streptococcus. Organism distribution varied by age and length of hospitalization, suggesting tailored treatment approaches for pediatric bacterial conjunctivitis.
Area of Science:
- Ophthalmology
- Pediatric Infectious Diseases
- Microbiology
Background:
- Acute bacterial conjunctivitis is a common pediatric infection.
- Understanding the causative organisms is crucial for effective treatment.
- Previous studies primarily focused on outpatient settings.
Purpose of the Study:
- To identify the spectrum of bacteria responsible for acute bacterial conjunctivitis in hospitalized children.
- To compare findings with existing literature from outpatient populations.
Main Methods:
- Retrospective chart review of hospitalized children with confirmed bacterial conjunctivitis.
- Analysis of conjunctival culture results from 59 patients (107 isolates).
Main Results:
- Coagulase-negative Staphylococcus (59.3%) and viridans Streptococcus (47.5%) were the most frequent isolates.
- Staphylococcus aureus and Haemophilus influenzae were more prevalent in non-neonates.
- Gram-negative bacilli and methicillin-resistant Staphylococcus species were associated with longer hospital stays.
Conclusions:
- The microbial spectrum of acute bacterial conjunctivitis in hospitalized children differs from outpatient settings.
- Culture and sensitivity testing before empiric antibiotic therapy may optimize treatment for pediatric bacterial conjunctivitis.
Purpose:
To determine the spectrum of organisms causing acute bacterial conjunctivitis in hospitalized children at a tertiary care referral center.
Design:
Retrospective chart review.
Methods:
Charts of hospitalized children with positive conjunctival cultures were reviewed, and patients with clinical description of conjunctivitis were studied.
Results:
One hundred and seven isolates from 59 patients were included in the study. The most common organisms cultured were coagulase-negative Staphylococcus (59.3% of patients), viridans Streptococcus (47.5%), and Staphylococcus aureus (20.3%). The type of organisms differed based on age, with S. aureus and Haemophilus influenzae being more common in nonneonates. Gram-negative bacilli and methicillin-resistant Staphylococcus species were more common in patients hospitalized longer than two days.
Conclusions:
The distribution of bacterial organisms causing acute bacterial conjunctivitis in our hospitalized children differs from that of previous reports in the outpatient setting. Conjunctival swabbing for culture and sensitivities before instituting empiric broad-spectrum antibiotic therapy may be useful.
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