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Updated: Jul 19, 2026

Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload
Published on: March 14, 2017
State-of-the-art blood saving techniques
1Institute of Anaesthesiology, University Hospital Zürich, Zürich, Switzerland. donat.spahn@ifa.usz.ch
Abstract:
Preoperative autologous donation, the use of erythropoietin, acute normovolaemic haemodilution, acceptance of minimal perioperative haemoglobin levels, the use of specific drugs (aprotinin, antifibrinolytics), cell saving and a meticulous surgical technique aimed at minimizing blood loss have all been described as blood saving techniques. Each has proved effective in reducing the need for allogeneic blood transfusions. With an appropriate selection of patients, all techniques can be used efficiently.
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