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Updated: Jul 19, 2026

Technical Refinement of a Bilateral Renal Ischemia-Reperfusion Mouse Model for Acute Kidney Injury Research
Published on: November 3, 2023
Perioperative renal protection
1Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Boston, Massachusetts 02115, USA.
Abstract:
Acute renal failure continues to complicate the postoperative courses of our vascular and cardiac surgical patients, dramatically increasing mortality and decreasing quality of life when it occcurs. In spite of better understanding of the disease, few gains have been made in its prevention. We review its pathophysiology and discuss the most recent developments that may eventually lead to perioperative renal protection.
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