Related Experiment Video
Updated: Jul 19, 2026

Quantitating Iron Transport Across the Mouse Placenta In Vivo Using Nonradioactive Iron Isotopes
Published on: May 10, 2022
Iron homeostasis
Nancy C Andrews1, Paul J Schmidt
1Children's Hospital Boston and Harvard Medical School, Karp Family Research Laboratories, Boston, Massachusetts 02115, USA. nancy_andrews@hms.harvard.edu
Abstract:
Iron is needed by all mammalian cells but is toxic in excess. Specialized transport mechanisms conduct iron across cellular membranes. These are regulated to ensure homeostasis both systemically in living organisms and within individual cells. Over the past decade, major advances have been made in identifying and characterizing the proteins involved in the transport, handling, and homeostatic regulation of iron. Molecular understanding of these processes has provided important insights into the pathophysiology of human iron disorders.
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