Study of an error-prone hypercycle formed from two kinetically distinguishable species
Related Experiment Video
Updated: Jul 19, 2026

Rare Event Detection Using Error-corrected DNA and RNA Sequencing
Published on: August 3, 2018
M A Andrade1, A J García-Tejedor, F Montero
1Departamento de Bioquímica y Biologia Molecular I, Facultad de Ciencias Químicas, Universidad Complutense de Madrid, 28040 Madrid, Spain.
Abstract:
Asymmetry within both the amplification factor values (Ak) and cross-catalytic hypercyclic constant (Kjk) and its influence on the stability of a two-membered error-prone hypercycle has been exhaustively studied from a deterministic point of view and the bifurcation diagram as a function of the quality factor (Q) has been obtained. In the more general case, several Q critical values appear, changing their relative position in the diagram depending on the Ak and Kjk values. The order of the Q critical values affects both the general properties of the system and the stability of the hypercyclic organization. The importance of this asymmetry in the selective and evolutionary properties of the hypercycle is also discussed.
More Related Videos
14:27Steady-state, Pre-steady-state, and Single-turnover Kinetic Measurement for DNA Glycosylase Activity
Published on: August 19, 2013
07:59Alignment of Synchronized Time-Series Data Using the Characterizing Loss of Cell Cycle Synchrony Model for Cross-Experiment Comparisons
Published on: June 9, 2023
Related Concept Videos
Woodward–Hoffmann Selection Rules and Microscopic Reversibility
Transition State Theory
Thermal and Photochemical Electrocyclic Reactions: Overview
Photochemical Electrocyclic Reactions: Stereochemistry
Selection Rules: Photochemical Activation
Pericyclic Reactions: Introduction
Pericyclic reactions can be classified into three categories: electrocyclic reactions, cycloaddition reactions, and sigmatropic rearrangements. Electrocyclic reactions and sigmatropic rearrangements are...
Dynamic Equilibrium