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Colonization and infection with vancomycin-resistant Enterococcus among patients with cancer
Madonna J Matar1, Jeffrey Tarrand, Issam Raad
1Department of Infectious Diseases, Infection Control, and Employee Health, Houston, TX 77030, USA. madonne@inco.com.lb
Abstract:
Vancomycin-resistant enterococci (VRE) cause substantial morbidity and mortality in immune-suppressed patients. In a retrospective review, VRE fecal colonization was documented in 4.7% (99 of 2115) of patients screened, with 5.4% of patients with leukemia, 4.9% of hematopoietic stem cell transplantation recipients, and 2.2% of patients with lymphoma being colonized. Among the 99 patients with VRE colonization, 29 (29.29%) developed bacteremia, and there were 32 episodes of VRE infection at other sites. The rate of VRE bacteremia in solid tumor patients (0.12%) was significantly lower (P
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