Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Cardiac surgery and the coagulation system.

W Dietrich1

  • 1German Heart Centre Munich, Institute for Anaesthesiology, Munich, Germany. Dietrich@dhm.mhn.de

Current Opinion in Anaesthesiology
|October 4, 2006
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Does preoperative locally applied estrogen treatment facilitate prolapse-associated symptoms in postmenopausal women with symptomatic pelvic organ prolapse? A randomised controlled double-masked, placebo-controlled, multicentre study.

BJOG : an international journal of obstetrics and gynaecology·2021
Same author

[Neurological aspects of intensive care: stroke, intracerebral hemorrhage, meningitis, status epilepticus].

Deutsche medizinische Wochenschrift (1946)·2013
Same author

[Increased intracranial pressure and brain edema].

Der Anaesthesist·2013
Same author

[Increased intracranial pressure and brain edema].

Medizinische Klinik, Intensivmedizin und Notfallmedizin·2013
Same author

[The first 24 hours - the unconscious patient from the neurologist's viewpoint].

Deutsche medizinische Wochenschrift (1946)·2012
Same author

Is it time to implement preoperative platelet function testing before invasive procedures?

British journal of anaesthesia·2011

This review examines the activation of the hemostatic system during cardiopulmonary bypass, highlighting the interplay between hemostasis and inflammation. It discusses new anticoagulation strategies and established drug approaches to reduce hemostatic activation, offering future research perspectives.

Area of Science:

  • Cardiovascular Science
  • Hematology
  • Inflammation Research

Background:

  • Cardiopulmonary bypass (CPB) involves complex interactions of the hemostatic system.
  • Understanding the relationship between hemostasis and inflammation during CPB is crucial for patient outcomes.
  • Heparin is the standard anticoagulant, but alternatives are being explored.

Purpose of the Study:

  • To review the activation of the hemostatic system during CPB.
  • To examine the interaction between hemostasis and inflammation.
  • To discuss novel anticoagulation strategies and established drug approaches.

Main Methods:

  • Literature review of studies on hemostasis during CPB.
  • Analysis of the interplay between coagulation and inflammatory cascades.

Related Experiment Videos

  • Evaluation of current and emerging therapeutic strategies.

    • Main Results:

    • CPB activates the haemostatic system, involving complex cascade interactions.
    • The relationship between haemostasis and inflammation during CPB is a key area of investigation.
    • Established drug approaches effectively reduce haemostatic activation.

    Conclusions:

    • Novel anticoagulation strategies for CPB are emerging.
    • Established drugs modulating haemostasis show potential for influencing inflammatory responses.
    • Further research into the haemostasis-inflammation axis during CPB is warranted.