Pulmonary transplantation

Anesthetic technique for pulmonary transplantation varies with recipient's underlying lung disease, procedure performed and regional practice. The pulmonary allograft is vulnerable to mechanical and biochemical injury throughout the harvesting, preservation and engraftment procedures. Mechanisms of allograft injury are reviewed, with suggestions for incorporation of strategies to minimize injury into clinical practice. Particular emphasis is placed on the use of nitric oxide for treatment of reperfusion injury.