Related Experiment Video
Updated: Jul 19, 2026

In Vitro Method to Control Concentrations of Halogenated Gases in Cultured Alveolar Epithelial Cells
Published on: October 23, 2018
Is pulmonary aspiration still an important problem in anesthesia?
1Department of Anesthesiology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA. warner.mark@mayo.edu
Pulmonary aspiration during surgery is rare but can be severe, especially for elderly or very sick patients. Children generally experience less severe outcomes from aspiration events.
Area of Science:
- Anesthesiology
- Critical Care Medicine
- Pulmonary Medicine
Background:
- Pulmonary aspiration during anesthesia is a rare but serious complication.
- Severe patient outcomes, including death, can result from aspiration events.
- Risk factors for severe pulmonary morbidity after aspiration are not fully elucidated.
Purpose of the Study:
- To review the incidence and impact of perioperative pulmonary aspiration.
- To identify patient populations at greatest risk for severe outcomes following aspiration.
- To compare morbidity associated with aspiration in different age groups.
Main Methods:
- Review of recent studies on perioperative pulmonary aspiration.
- Analysis of patient data to identify risk factors for severe pulmonary morbidity.
- Comparison of aspiration-related outcomes in pediatric versus adult populations.
Main Results:
- Perioperative pulmonary aspiration occurs infrequently, estimated at 1:2000-3000 general anesthetics.
- Patients with American Society of Anesthesiologists physical classification 3 or greater are at higher risk for severe pulmonary complications.
- Elderly patients and those with significant comorbidities face increased risks.
- Children generally exhibit less morbidity from pulmonary aspiration compared to adults.
Conclusions:
- While rare, perioperative pulmonary aspiration poses a significant risk, particularly for vulnerable patient groups.
- Identifying high-risk patients, such as the elderly and those with severe systemic illness, is crucial for prevention and management strategies.
- Pediatric patients appear to tolerate aspiration events with lower morbidity.
Related Concept Videos
Inhalational Anesthetics: Overview
Respiratory Assessment: Purpose and Indications
Objectives and Importance:
The primary goal of respiratory assessment is to evaluate patients at early risk of clinical deterioration. Since respiratory distress often precedes other signs of declining health, breathing patterns and sounds become a...
Pneumonia V: Nursing management and Prevention
The nurse must practice strict medical asepsis and adhere to infection control guidelines to minimize healthcare-associated infections.
Enhance airway patency
Position the patient correctly to facilitate drainage of the affected lung segments. Manual or mechanical percussion and vibration can also be employed.
Endoscopic Studies II: Thoracocentesis
Description
Excess pleural fluid or air may accumulate in some respiratory disorders in the thoracic cavity. To treat pleural effusion, a physician conducts thoracentesis by carefully piercing the chest wall and entering...
Cardiopulmonary Resuscitation II: ACLS Airway Management
Sputum Studies II: Culture and Sensitivity
Sputum culture and sensitivity is a medical procedure used to diagnose bacterial infections in the respiratory tract and select the most appropriate antibiotics for treatment. This process involves analyzing sputum samples of thick and opaque secretions produced in the lungs and airways. These samples are collected from patients and then sent to the laboratory for analysis.
The test can identify various pathogens responsible for respiratory infections, including Streptococcus,...

