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Updated: Jul 19, 2026

Integrated Compensatory Responses in a Human Model of Hemorrhage
Published on: November 20, 2016
Blood conservation in patients undergoing non-cardiac surgery
1Department of Medicine, Washington University School of Medicine, St Louis, MO 63110-1093, USA. goodnough@labmed.wustl.edu
Abstract:
Concerns about the safety, inventory, and cost of allogeneic blood have led to a renewed interest in blood conservation. Autologous blood collection techniques, including preoperative autologous donation, acute normovolemic hemodilution, and perioperative blood recovery are routinely used as alternatives to allogeneic transfusion. In the future, these techniques may be combined with pharmacological strategies, such as presurgical erythropoietin therapy or red cell substitutes, to reduce further the need for allogeneic blood.
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